Assessment of hospital-level adjusted breast cancer sentinel lymph node positivity rates

Elizabeth R. Berger, Karl Y. Bilimoria, Christine V. Kinnier, Christina A. Minami, Kevin P. Bethke, Nora M. Hansen, Ryan P. Merkow, David P. Winchester, Anthony D. Yang*

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Background/Objectives: Proficiency of performing sentinel lymph node biopsy (SLNB) for breast cancer varies among hospitals and may be reflected in the hospital's SLNB positivity rate. Our objectives were to examine whether hospital characteristics are associated with variation in SLNB positivity rates and whether hospitals with lower-than-expected SLNB positivity rates have worse patient survival. Methods: Using the National Cancer Data Base, stage I to III breast cancer patients were identified (2004-2012). Hospital-level SLNB positivity rates were adjusted for tumor and patient factors. Hospitals were divided into terciles of SLNB positivity rates (lower-, higher-, as-expected). Hospital characteristics and survival were examined across terciles. Results: Of 438 610 SLNB patients (from 1357 hospitals), 78 104 had one or more positive SLN (21.3%). Hospitals in the low and high terciles were more likely to be low volume (low: RRR, 4.40; 95% CI, 2.89-6.57; P < 0.001; and high: RRR, 1.79; 95% CI, 1.21-2.64; P < 0.001) compared to hospitals with as-expected (middle tercile) SLNB positivity rates. Stage I patients at low- and high-tercile hospitals had statistically worse survival. Conclusions: There is a wide variation in hospital SLNB positivity rates. Hospitals with lower- or higher-than-expected SLNB positivity rates were associated with survival differences. Hospital SLNB positivity rates may be a novel ‘process measure’ to report to hospitals for internal quality assessment.

Original languageEnglish (US)
Pages (from-to)101-108
Number of pages8
JournalJournal of surgical oncology
Volume119
Issue number1
DOIs
StatePublished - Jan 1 2019

Keywords

  • breast cancer
  • health outcomes
  • node biopsy
  • process measures
  • quality metric
  • sentinel lymph

ASJC Scopus subject areas

  • Surgery
  • Oncology

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