Assessment of hypoallergenicity of ten skincare products

Staci Brandt*, Peter Lio

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Sensitive skin is a common skin complaint frequently associated with skin diseases or adverse reactions to cosmetic products. Manufacturers have produced numerous products targeted for patients with sensitive skin and frequently label these products as being hypoallergenic. This term implies that the product may be less likely to cause an allergic reaction and be better suited for those with sensitive skin. However, there is no federal regulatory definition of this term and products may not have clinical support of their claim. Patch testing ingredients is frequently done to identify potential irritants; however, patch-testing product formulations may provide more realistic expectations about potential skin sensitivity and help support claims of hypoallergenicity. Ten skincare products were assessed for their sensitizing potential and hypoallergenicity in 14 repeat insult patch test clinical studies, involving over 2,000 subjects. In these studies, the products were deemed to be hypoallergenic if there was no evidence of sensitization or allergic reactions. The results from these trials demonstrated that all ten products were well tolerated, showed no sensitization or allergic reactions, and support claims of hypoallergenicity.

Original languageEnglish (US)
Pages (from-to)264-266
Number of pages3
JournalJournal of Drugs in Dermatology
Issue number3
StatePublished - Mar 2014

ASJC Scopus subject areas

  • Dermatology


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