Assessment of the association between habitual salt intake and high blood pressure: Methodological problems

Kiang Liu*, Richard Cooper, Jeffrey Mckeever, Patricia Makeever, Robert Byington, Ivan Soltero, Rose Stamler, Flora Gosch, Elizabeth Stevens, Jeremiah Stamler

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

227 Scopus citations

Abstract

Despite the finding in cross-cultural comparisons that habitual sodium intake correlates with levels of blood pressure, similar studies from within population groups have yielded inconsistent results. The data presented in this report indicate that in industrialized societies the high degree of intra-individual variability of sodium intake, compared to much smaller inter-individual differences, may obscure potential biological correlations. A quantitative statistical method is presented to assess and minimize the effect of the large Intra-individual variation in daily urinary sodium excretion.

Original languageEnglish (US)
Pages (from-to)219-226
Number of pages8
JournalAmerican journal of epidemiology
Volume110
Issue number2
StatePublished - Aug 1 1979

Keywords

  • Blood pressure
  • Hypertension
  • Sodium
  • Urine

ASJC Scopus subject areas

  • Epidemiology

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