Assessment of variables associated with smoking cessation in crohn's disease

Yvette Leung*, Gil G. Kaplan, Kevin P. Rioux, James Hubbard, Sarah Kamhawi, Lidia Stasiak, Russell D. Cohen, Shane M. Devlin, Remo Panaccione, Stephen B. Hanauer, David T. Rubin

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Background Patients with Crohn's disease (CD) who smoke have a more complicated disease course. Aims Our primary objective was to assess smoking related variables that were associated with smoking cessation versus continued smoking in patients with CD. Methods A multi-center study identified CD patients who were seen at the University of Chicago and University of Calgary IBD clinics. Patients were categorized into three subgroups: lifetime non-smokers, current smokers, or ex-smokers. Participants completed questionnaires assessing their cigarette smoking behavior. Current smokers were prospectively followed for 6 months to assess smoking status and attempts to quit. Logistic regression analysis was performed to identify factors associated with smoking cessation. Results Three hundred patients were enrolled with 148 identifying themselves as lifetime non-smokers, 70 as current smokers, and 82 as ex-smokers. Patients who reported their first cigarette within 5 min of waking were more likely to be current smokers (OR = 21; 95% CI 3.94-107.3) as compared to patients who waited greater than 60 min. Current smokers were more likely to have one or more household members who smoked compared to ex-smokers (P\0.05). Nearly half (49%) of the current smokers were in the precontemplation stage of change (i.e. no intention to quit smoking). At the 6-month followup, only 11% reported they quit smoking. Conclusions Patients who report a short time to first cigarette in the morning may have more difficulty in smoking cessation. Current smokers were more likely to have another smoker in the household compared to ex-smokers. Current smokers had low levels of motivation to quit smoking and consequently with no intervention, very few quit 6 months after the baseline assessment.

Original languageEnglish (US)
Pages (from-to)1026-1032
Number of pages7
JournalDigestive diseases and sciences
Issue number4
StatePublished - Apr 2012


  • Cigarette smoking
  • Crohn's disease
  • Nicotine dependence
  • Smoking cessation

ASJC Scopus subject areas

  • Physiology
  • Gastroenterology


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