Abstract
The chromosomal location of SCN5A, the gene encoding the principal voltage-gated Na+ channel expressed in human heart, has been determined by three independent methodologies: Somatic cell hybrid mapping, chromosomal micro-dissection-polymerase chain reaction, and fluorescence in situ hybridization. The SCN5A gene was assigned to the short arm of chromosome 3 (band 3p21) by all three approaches. These data are further evidence that striated muscle Na+ channel genes are dispersed in the genome.
Original language | English (US) |
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Pages (from-to) | 67-70 |
Number of pages | 4 |
Journal | Cytogenetics and Cell Genetics |
Volume | 68 |
Issue number | 1-2 |
DOIs | |
State | Published - 1995 |
ASJC Scopus subject areas
- Genetics
- Cell Biology