TY - JOUR
T1 - Association between high-density mapping of atypical atrial flutter, clinical outcomes and healthcare utilization
AU - Sink, Joshua
AU - Culler, Kasen
AU - Uppalapati, Lakshmi
AU - Lancki, Nicola
AU - Peigh, Graham
AU - Lohrmann, Graham
AU - Elsayed, Mahmoud
AU - Carneiro, Herman
AU - Baman, Jayson
AU - Pfenniger, Anna
AU - Patil, Kaustubha Dilip
AU - Verma, Nishant
AU - Arora, Rishi K
AU - Kim Koss, Susan S
AU - Chicos, Alexandru B.
AU - Lin, Albert Chao-tun
AU - Knight, Bradley Paul
AU - Passman, Rod S
N1 - Publisher Copyright:
© 2024 The Author(s). Journal of Cardiovascular Electrophysiology published by Wiley Periodicals LLC.
PY - 2024
Y1 - 2024
N2 - Background: Success of atypical atrial flutter (AAFL) ablation has historically been limited by difficulty mapping the complex re-entrant circuits involved. While high-density (HD) mapping has become commonplace in clinical practice, there are limited data on outcomes of HD versus non-HD mapping for AAFL ablation. Objective: To compare clinical outcomes and healthcare utilization using HD mapping versus non-HD mapping for AAFL ablation. Methods: Retrospective analysis of all AAFL procedures between 2005 and 2022 at an academic medical center was conducted. Procedures utilizing a 16-electrode HD Grid catheter and Precision mapping system were compared to procedures using prior generation 10–20 electrode spiral catheters and the Velocity system (Abbott, IL). Cox regression models and Poisson regression models were utilized to examine procedural and healthcare utilization outcomes. Models were adjusted for left ventricular ejection fraction, CHA2DS2-VASc, and history of prior ablation. Results: There were 108 patients (62% HD mapping) included in the analysis. Baseline clinical characteristics were similar between groups. Use of HD mapping was associated with a higher rate of AAFL circuit delineation (92.5% vs. 76%; p =.014) and a greater adjusted procedure success rate, defined as non-inducibility at procedure end, (aRR (95% CI) 1.26 (1.02–1.55) p =.035) than non-HD mapping. HD mapping was also associated with a lower rate of ED visits (aIRR (95% CI) 0.32 (0.14–0.71); p =.007) and hospitalizations (aIRR (95% CI) 0.32 (0.14–0.68); p =.004) for AF/AFL/HF through 1 year. While there was a lower rate of recurrent AFL through 1 year among HD mapping cases (aHR (95% CI) 0.60 (0.31–1.16) p =.13), statistical significance was not met likely due to the low sample size and higher rate of ambulatory rhythm monitoring in the HD group (61% vs. 39%, p =.025). Conclusion: Compared to non-HD mapping, AAFL ablation with HD mapping is associated with improvements in the ability to define the AAFL circuit, greater procedural success, and a reduction in the number of ED visits and hospitalization for AF/AFL/HF.
AB - Background: Success of atypical atrial flutter (AAFL) ablation has historically been limited by difficulty mapping the complex re-entrant circuits involved. While high-density (HD) mapping has become commonplace in clinical practice, there are limited data on outcomes of HD versus non-HD mapping for AAFL ablation. Objective: To compare clinical outcomes and healthcare utilization using HD mapping versus non-HD mapping for AAFL ablation. Methods: Retrospective analysis of all AAFL procedures between 2005 and 2022 at an academic medical center was conducted. Procedures utilizing a 16-electrode HD Grid catheter and Precision mapping system were compared to procedures using prior generation 10–20 electrode spiral catheters and the Velocity system (Abbott, IL). Cox regression models and Poisson regression models were utilized to examine procedural and healthcare utilization outcomes. Models were adjusted for left ventricular ejection fraction, CHA2DS2-VASc, and history of prior ablation. Results: There were 108 patients (62% HD mapping) included in the analysis. Baseline clinical characteristics were similar between groups. Use of HD mapping was associated with a higher rate of AAFL circuit delineation (92.5% vs. 76%; p =.014) and a greater adjusted procedure success rate, defined as non-inducibility at procedure end, (aRR (95% CI) 1.26 (1.02–1.55) p =.035) than non-HD mapping. HD mapping was also associated with a lower rate of ED visits (aIRR (95% CI) 0.32 (0.14–0.71); p =.007) and hospitalizations (aIRR (95% CI) 0.32 (0.14–0.68); p =.004) for AF/AFL/HF through 1 year. While there was a lower rate of recurrent AFL through 1 year among HD mapping cases (aHR (95% CI) 0.60 (0.31–1.16) p =.13), statistical significance was not met likely due to the low sample size and higher rate of ambulatory rhythm monitoring in the HD group (61% vs. 39%, p =.025). Conclusion: Compared to non-HD mapping, AAFL ablation with HD mapping is associated with improvements in the ability to define the AAFL circuit, greater procedural success, and a reduction in the number of ED visits and hospitalization for AF/AFL/HF.
KW - atypical atrial flutter
KW - healthcare utilization
KW - high density mapping
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U2 - 10.1111/jce.16355
DO - 10.1111/jce.16355
M3 - Article
C2 - 38965878
AN - SCOPUS:85197876437
SN - 1045-3873
JO - Journal of cardiovascular electrophysiology
JF - Journal of cardiovascular electrophysiology
ER -