Association between type D personality and in-stent restenosis in patients treated with percutaneous coronary intervention: A mediation analysis of dietary patterns

Yini Wang, Sijia Zhang, Gai Zhang, Bo Yu, Xueqin Gao, Zhenguo Dai, Xiuxian Yang, Xiaohui Qiu, Zhengxue Qiao, Jiawei Zhou, Ping Lin, Deyu Fang, Yanjie Yang*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: Type D personality is a psychosocial risk factor for cardiovascular events and in-stent restenosis (ISR), but the mechanisms involved are not well understood. This study aimed to evaluate the effects of dietary patterns on the association between Type D personality and ISR in patients with coronary artery disease treated with percutaneous coronary intervention (PCI). Methods: This cross-sectional study comprised a total of 230 post-PCI patients who were assessed for Type D personality, depression, dietary patterns, physical activity and medication adherence via self-administered questionnaires. ISR was assessed by coronary angiography. Results: Type D personality (odds ratio [OR], 3.35; 95% confidence interval [CI], 1.05-10.71, p=0.042), low fruit intake (OR, 0.30; 95% CI, 0.12–0.68, p=0.008) and low vegetable intake (OR, 0.48, 95% CI, 0.27–0.91, p=0.021) were independent risk factors for ISR after adjustment for psychosocial, lifestyle and cardiovascular risk factors. Mediation analyses revealed that Type D personality had a significant direct effect on the development of ISR (p<0.05). In addition, nutrients in fruits and vegetables, including vitamin C, vitamin E and fiber, were important mediators of the relationship between Type D personality and ISR (p<0.05), the percentage of total indirect effect was 24.65%. Conclusions: These findings suggested that the low intake of fruit and vegetables in Type D patients can predict ISR. The healthy dietary interventions to supply vitamin C, vitamin E and fiber may help to improve the prognosis in post-PCI patients with Type D personality.

Original languageEnglish (US)
Article number110244
JournalJournal of Psychosomatic Research
Volume138
DOIs
StatePublished - Nov 2020

ASJC Scopus subject areas

  • Clinical Psychology
  • Psychiatry and Mental health

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