Association of Cervical Effacement with the Rate of Cervical Change in Labor among Nulliparous Women

Elizabeth S. Langen*, Steven J. Weiner, Steven L. Bloom, Dwight J. Rouse, Michael W. Varner, Uma M. Reddy, Susan M. Ramin, Steve N. Caritis, Alan M Peaceman, Yoram Sorokin, Anthony Sciscione, Marshall W. Carpenter, Brian M. Mercer, John M. Thorp, Fergal D. Malone, Jay D. Iams

*Corresponding author for this work

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

OBJECTIVE: To assess the association of cervical effacement with the rate of intrapartum cervical change among nulliparous women. METHODS: We conducted a secondary analysis of a prospective trial of intrapartum fetal pulse oximetry. For women who had vaginal deliveries, interval-censored regression was used to estimate the time to dilate at 1-cm intervals. For each given centimeter of progressive cervical dilation, women were divided into those who had achieved 100% cervical effacement and those who had not. The analysis was performed separately for women in spontaneous labor and those who were given oxytocin. RESULTS: A total of 3,902 women were included in this analysis, 1,466 (38%) who underwent labor induction, 1,948 (50%) who underwent labor augmentation (combined for the analysis), and 488 (13%) who labored spontaneously. For women in spontaneous labor, the time to dilate 1 cm was shorter for those who were 100% effaced starting at 4 cm of cervical dilation (P5.01 to ,.001). For women who received oxytocin, the time to dilate 1 cm was shorter for those who were 100% effaced throughout labor (P,.001). CONCLUSION: The rate of cervical dilation among nulliparous women is associated with not only the degree of cervical dilation, but also with cervical effacement.

Original languageEnglish (US)
Pages (from-to)489-495
Number of pages7
JournalObstetrics and gynecology
Volume127
Issue number3
DOIs
StatePublished - Mar 1 2016

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Dilatation
Oxytocin
Induced Labor
Oximetry

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Langen, E. S., Weiner, S. J., Bloom, S. L., Rouse, D. J., Varner, M. W., Reddy, U. M., ... Iams, J. D. (2016). Association of Cervical Effacement with the Rate of Cervical Change in Labor among Nulliparous Women. Obstetrics and gynecology, 127(3), 489-495. https://doi.org/10.1097/AOG.0000000000001299
Langen, Elizabeth S. ; Weiner, Steven J. ; Bloom, Steven L. ; Rouse, Dwight J. ; Varner, Michael W. ; Reddy, Uma M. ; Ramin, Susan M. ; Caritis, Steve N. ; Peaceman, Alan M ; Sorokin, Yoram ; Sciscione, Anthony ; Carpenter, Marshall W. ; Mercer, Brian M. ; Thorp, John M. ; Malone, Fergal D. ; Iams, Jay D. / Association of Cervical Effacement with the Rate of Cervical Change in Labor among Nulliparous Women. In: Obstetrics and gynecology. 2016 ; Vol. 127, No. 3. pp. 489-495.
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title = "Association of Cervical Effacement with the Rate of Cervical Change in Labor among Nulliparous Women",
abstract = "OBJECTIVE: To assess the association of cervical effacement with the rate of intrapartum cervical change among nulliparous women. METHODS: We conducted a secondary analysis of a prospective trial of intrapartum fetal pulse oximetry. For women who had vaginal deliveries, interval-censored regression was used to estimate the time to dilate at 1-cm intervals. For each given centimeter of progressive cervical dilation, women were divided into those who had achieved 100{\%} cervical effacement and those who had not. The analysis was performed separately for women in spontaneous labor and those who were given oxytocin. RESULTS: A total of 3,902 women were included in this analysis, 1,466 (38{\%}) who underwent labor induction, 1,948 (50{\%}) who underwent labor augmentation (combined for the analysis), and 488 (13{\%}) who labored spontaneously. For women in spontaneous labor, the time to dilate 1 cm was shorter for those who were 100{\%} effaced starting at 4 cm of cervical dilation (P5.01 to ,.001). For women who received oxytocin, the time to dilate 1 cm was shorter for those who were 100{\%} effaced throughout labor (P,.001). CONCLUSION: The rate of cervical dilation among nulliparous women is associated with not only the degree of cervical dilation, but also with cervical effacement.",
author = "Langen, {Elizabeth S.} and Weiner, {Steven J.} and Bloom, {Steven L.} and Rouse, {Dwight J.} and Varner, {Michael W.} and Reddy, {Uma M.} and Ramin, {Susan M.} and Caritis, {Steve N.} and Peaceman, {Alan M} and Yoram Sorokin and Anthony Sciscione and Carpenter, {Marshall W.} and Mercer, {Brian M.} and Thorp, {John M.} and Malone, {Fergal D.} and Iams, {Jay D.}",
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Langen, ES, Weiner, SJ, Bloom, SL, Rouse, DJ, Varner, MW, Reddy, UM, Ramin, SM, Caritis, SN, Peaceman, AM, Sorokin, Y, Sciscione, A, Carpenter, MW, Mercer, BM, Thorp, JM, Malone, FD & Iams, JD 2016, 'Association of Cervical Effacement with the Rate of Cervical Change in Labor among Nulliparous Women', Obstetrics and gynecology, vol. 127, no. 3, pp. 489-495. https://doi.org/10.1097/AOG.0000000000001299

Association of Cervical Effacement with the Rate of Cervical Change in Labor among Nulliparous Women. / Langen, Elizabeth S.; Weiner, Steven J.; Bloom, Steven L.; Rouse, Dwight J.; Varner, Michael W.; Reddy, Uma M.; Ramin, Susan M.; Caritis, Steve N.; Peaceman, Alan M; Sorokin, Yoram; Sciscione, Anthony; Carpenter, Marshall W.; Mercer, Brian M.; Thorp, John M.; Malone, Fergal D.; Iams, Jay D.

In: Obstetrics and gynecology, Vol. 127, No. 3, 01.03.2016, p. 489-495.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Association of Cervical Effacement with the Rate of Cervical Change in Labor among Nulliparous Women

AU - Langen, Elizabeth S.

AU - Weiner, Steven J.

AU - Bloom, Steven L.

AU - Rouse, Dwight J.

AU - Varner, Michael W.

AU - Reddy, Uma M.

AU - Ramin, Susan M.

AU - Caritis, Steve N.

AU - Peaceman, Alan M

AU - Sorokin, Yoram

AU - Sciscione, Anthony

AU - Carpenter, Marshall W.

AU - Mercer, Brian M.

AU - Thorp, John M.

AU - Malone, Fergal D.

AU - Iams, Jay D.

PY - 2016/3/1

Y1 - 2016/3/1

N2 - OBJECTIVE: To assess the association of cervical effacement with the rate of intrapartum cervical change among nulliparous women. METHODS: We conducted a secondary analysis of a prospective trial of intrapartum fetal pulse oximetry. For women who had vaginal deliveries, interval-censored regression was used to estimate the time to dilate at 1-cm intervals. For each given centimeter of progressive cervical dilation, women were divided into those who had achieved 100% cervical effacement and those who had not. The analysis was performed separately for women in spontaneous labor and those who were given oxytocin. RESULTS: A total of 3,902 women were included in this analysis, 1,466 (38%) who underwent labor induction, 1,948 (50%) who underwent labor augmentation (combined for the analysis), and 488 (13%) who labored spontaneously. For women in spontaneous labor, the time to dilate 1 cm was shorter for those who were 100% effaced starting at 4 cm of cervical dilation (P5.01 to ,.001). For women who received oxytocin, the time to dilate 1 cm was shorter for those who were 100% effaced throughout labor (P,.001). CONCLUSION: The rate of cervical dilation among nulliparous women is associated with not only the degree of cervical dilation, but also with cervical effacement.

AB - OBJECTIVE: To assess the association of cervical effacement with the rate of intrapartum cervical change among nulliparous women. METHODS: We conducted a secondary analysis of a prospective trial of intrapartum fetal pulse oximetry. For women who had vaginal deliveries, interval-censored regression was used to estimate the time to dilate at 1-cm intervals. For each given centimeter of progressive cervical dilation, women were divided into those who had achieved 100% cervical effacement and those who had not. The analysis was performed separately for women in spontaneous labor and those who were given oxytocin. RESULTS: A total of 3,902 women were included in this analysis, 1,466 (38%) who underwent labor induction, 1,948 (50%) who underwent labor augmentation (combined for the analysis), and 488 (13%) who labored spontaneously. For women in spontaneous labor, the time to dilate 1 cm was shorter for those who were 100% effaced starting at 4 cm of cervical dilation (P5.01 to ,.001). For women who received oxytocin, the time to dilate 1 cm was shorter for those who were 100% effaced throughout labor (P,.001). CONCLUSION: The rate of cervical dilation among nulliparous women is associated with not only the degree of cervical dilation, but also with cervical effacement.

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DO - 10.1097/AOG.0000000000001299

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