Association of labor induction or stimulation with infant mortality in women with failed versus successful trial of labor after prior cesarean

Han Yang Chen, Suneet P. Chauhan*, William A. Grobman, Cande V. Ananth, Anthony M. Vintzileos, Alfred Z. Abuhamad

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Objective: To compare infant mortality rates among women with a failed versus successful trial of labor after cesarean (TOLAC) following labor induction or stimulation. Study design: Using US linked birth and infant death cohort data (2000-2004), we identified women who delivered non-anomalous singleton births at 34-41 weeks with TOLAC whose labors were induced or stimulated. Multivariable log-binomial regression models were fitted to estimate the association between TOLAC success and infant mortality. Results: Of the 164,113 women who underwent TOLAC, 41% were unsuccessful. After adjustment for potential confounding factors, a failed TOLAC was associated with a 1.4 fold (95% confidence interval [CI] 1.1, 1.7) increased risk of infant mortality. Conclusions: Among women undergoing labor induction or stimulation, a failed TOLAC is associated with higher likelihood of infant mortality.

Original languageEnglish (US)
Pages (from-to)1162-1165
Number of pages4
JournalJournal of Maternal-Fetal and Neonatal Medicine
Volume26
Issue number12
DOIs
StatePublished - Aug 2013

Keywords

  • Infant mortality
  • Labor induction or augmentation
  • Trial of labor after cesarean

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

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