Association of nonsuppression of cortisol on the DST with primary polydipsia in chronic schizophrenia

Morris B. Goldman*, Lesley Blake, Robert C. Marks, Donald Hedeker, Daniel J. Luchins

*Corresponding author for this work

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

Thirteen polydipsic and 40 nonpolydipsic chronic schizophrenic patients received the dexamethasone suppression test while stabilized on psychotropic medication regimens. Thirty-eight percent (N=5) of those with polydipsia hut only 5% (N=2) of those without polydipsia were nonsuppressors of cartisol (i.e., had an abnormal response). It is suggested that hippocampal dysfunction could cause both polydipsia and cortisol dysregulation in these patients.

Original languageEnglish (US)
Pages (from-to)653-655
Number of pages3
JournalAmerican Journal of Psychiatry
Volume150
Issue number4
DOIs
StatePublished - Jan 1 1993

ASJC Scopus subject areas

  • Psychiatry and Mental health

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