Association of nonsuppression of cortisol on the DST with primary polydipsia in chronic schizophrenia

Morris B. Goldman; Lesley Blake; Robert C. Marks; Donald Hedeker; Daniel J. Luchins

doi:10.1176/ajp.150.4.653

Association of nonsuppression of cortisol on the DST with primary polydipsia in chronic schizophrenia

Morris B. Goldman^*, Lesley Blake, Robert C. Marks, Donald Hedeker, Daniel J. Luchins

^*Corresponding author for this work

Psychiatry and Behavioral Sciences

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

Thirteen polydipsic and 40 nonpolydipsic chronic schizophrenic patients received the dexamethasone suppression test while stabilized on psychotropic medication regimens. Thirty-eight percent (N=5) of those with polydipsia hut only 5% (N=2) of those without polydipsia were nonsuppressors of cartisol (i.e., had an abnormal response). It is suggested that hippocampal dysfunction could cause both polydipsia and cortisol dysregulation in these patients.

Original language	English (US)
Pages (from-to)	653-655
Number of pages	3
Journal	American Journal of Psychiatry
Volume	150
Issue number	4
DOIs	https://doi.org/10.1176/ajp.150.4.653
State	Published - 1993

ASJC Scopus subject areas

Psychiatry and Mental health

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1176/ajp.150.4.653

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abstract = "Thirteen polydipsic and 40 nonpolydipsic chronic schizophrenic patients received the dexamethasone suppression test while stabilized on psychotropic medication regimens. Thirty-eight percent (N=5) of those with polydipsia hut only 5% (N=2) of those without polydipsia were nonsuppressors of cartisol (i.e., had an abnormal response). It is suggested that hippocampal dysfunction could cause both polydipsia and cortisol dysregulation in these patients.",

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AU - Marks, Robert C.

AU - Hedeker, Donald

AU - Luchins, Daniel J.

PY - 1993

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AB - Thirteen polydipsic and 40 nonpolydipsic chronic schizophrenic patients received the dexamethasone suppression test while stabilized on psychotropic medication regimens. Thirty-eight percent (N=5) of those with polydipsia hut only 5% (N=2) of those without polydipsia were nonsuppressors of cartisol (i.e., had an abnormal response). It is suggested that hippocampal dysfunction could cause both polydipsia and cortisol dysregulation in these patients.

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Association of nonsuppression of cortisol on the DST with primary polydipsia in chronic schizophrenia

Abstract

ASJC Scopus subject areas

UN SDGs

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