Thirteen polydipsic and 40 nonpolydipsic chronic schizophrenic patients received the dexamethasone suppression test while stabilized on psychotropic medication regimens. Thirty-eight percent (N=5) of those with polydipsia hut only 5% (N=2) of those without polydipsia were nonsuppressors of cartisol (i.e., had an abnormal response). It is suggested that hippocampal dysfunction could cause both polydipsia and cortisol dysregulation in these patients.
ASJC Scopus subject areas
- Psychiatry and Mental health