TY - JOUR
T1 - Associations Between Asthma Control and Airway Obstruction and Performance of Activities of Daily Living in Older Adults with Asthma
AU - Woods, Eric C.
AU - O'Conor, Rachel
AU - Martynenko, Melissa
AU - Wolf, Michael S.
AU - Wisnivesky, Juan P.
AU - Federman, Alex D.
N1 - Funding Information:
Conflict of Interest: The editor in chief has reviewed the conflict of interest checklist provided by the authors and has determined that the authors have no financial or any other kind of personal conflicts with this paper. Dr. Wisnivesky is a member of the research board of EHE International and has received lecture fees from Novartis Pharmaceutical, consulting honoraria from UBC, and a research grant from GlaxoSmithKline. Funding was received from the National Heart, Lung, and Blood Institute (1R01HL096612–01). Author Contribution: Woods, Wolf, Wisnivesky, Federman: study design. O'Conor, Martynenko, Wolf, Wisnivesky, Federman: data acquisition. Woods, Federman: data analysis. Woods, O'Conor, Martynenko, Wolf, Wisnivesky, Federman: data interpretation. Woods: drafting of manuscript. O'Conor, Martynenko, Wolf, Wisnivesky, Federman: critical revision of intellectual content. Woods, O'Conor, Martynenko, Wolf, Wisnivesky, Federman: final manuscript approval. Sponsor's Role: The sponsor played no role in the design, methods, subject recruitment, data collection, analysis or preparation of this paper.
Publisher Copyright:
© 2016, Copyright the Authors Journal compilation © 2016, The American Geriatrics Society
PY - 2016/5/1
Y1 - 2016/5/1
N2 - Objectives: To determine the effect of asthma on functional limitations of older adults in the United States. Design: Analyses were conducted with data from the Asthma Beliefs and Literacy in the Elderly study, a prospective cohort study of people aged 60 and older with asthma. Setting: Participants were recruited from urban primary care and pulmonary specialty practices in New York City and Chicago between 2010 and 2012. Participants: Individuals aged 60 and older with asthma (380 women, 72 men, mean age 67.5 ± 6.8 (range 60–98), 40% Latino, 30% black). Measurements: Characteristics of participants with and without activity of daily living (ADL) limitations were compared using the chi-square test. Generalized estimating equations were used to model the relationships between poor asthma control (Asthma Control Questionnaire (ACQ) score >1.5) and severity of airway obstruction (forced expiratory volume in 1-second (FEV1)) and number of ADL limitations. Results: Participants with one or more ADL limitations were more likely to be female (90% vs 81%, P =.02) and Latino (58% vs 32%, P <.001), have less than a high school education (53% vs 27%, P <.001) and an income of $1,350 per month or less (79% vs 46%, P <.001), and be unmarried (78% vs 64%, P =.003). In the adjusted analysis, poorer ACQ scores (odds ratio (OR) = 1.6, 95% confidence interval (CI) = 1.0–2.4; P =.05) but not severity of airway obstruction (OR = 1.1, 95% CI = 0.6–1.9) was associated with greater ADL limitations. Conclusion: Older adults reporting poor asthma control are more likely to have ADL limitations than those with controlled asthma, although one-time spirometry may not adequately identify those at risk of physical impairment from asthma.
AB - Objectives: To determine the effect of asthma on functional limitations of older adults in the United States. Design: Analyses were conducted with data from the Asthma Beliefs and Literacy in the Elderly study, a prospective cohort study of people aged 60 and older with asthma. Setting: Participants were recruited from urban primary care and pulmonary specialty practices in New York City and Chicago between 2010 and 2012. Participants: Individuals aged 60 and older with asthma (380 women, 72 men, mean age 67.5 ± 6.8 (range 60–98), 40% Latino, 30% black). Measurements: Characteristics of participants with and without activity of daily living (ADL) limitations were compared using the chi-square test. Generalized estimating equations were used to model the relationships between poor asthma control (Asthma Control Questionnaire (ACQ) score >1.5) and severity of airway obstruction (forced expiratory volume in 1-second (FEV1)) and number of ADL limitations. Results: Participants with one or more ADL limitations were more likely to be female (90% vs 81%, P =.02) and Latino (58% vs 32%, P <.001), have less than a high school education (53% vs 27%, P <.001) and an income of $1,350 per month or less (79% vs 46%, P <.001), and be unmarried (78% vs 64%, P =.003). In the adjusted analysis, poorer ACQ scores (odds ratio (OR) = 1.6, 95% confidence interval (CI) = 1.0–2.4; P =.05) but not severity of airway obstruction (OR = 1.1, 95% CI = 0.6–1.9) was associated with greater ADL limitations. Conclusion: Older adults reporting poor asthma control are more likely to have ADL limitations than those with controlled asthma, although one-time spirometry may not adequately identify those at risk of physical impairment from asthma.
KW - activities of daily living
KW - asthma control
KW - older adults
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U2 - 10.1111/jgs.14108
DO - 10.1111/jgs.14108
M3 - Article
C2 - 27160645
AN - SCOPUS:84990222210
SN - 0002-8614
VL - 64
SP - 1046
EP - 1053
JO - Journal of the American Geriatrics Society
JF - Journal of the American Geriatrics Society
IS - 5
ER -