TY - JOUR
T1 - Associations between reliable changes in depression and changes in BMI, total body fatness and visceral adiposity during a 12-month weight loss trial
AU - Cameron, Natalie
AU - Godino, Job G.
AU - Skipper, Tricia
AU - Dillon, Lindsay
AU - Waalen, Jill
AU - Hill, Linda
AU - Patrick, Kevin
N1 - Publisher Copyright:
© 2018, Springer Nature Limited.
PY - 2019/9/1
Y1 - 2019/9/1
N2 - We investigated associations between changes in depression and body composition over a 12-month weight loss trial. Of the 298 adults (BMI > 27 m/kg2), 219 with complete depression and body composition data were included. A 10-item Center for Epidemiologic Studies Depression Scale measured depression; dual-energy X-ray absorptiometry measured body composition. Multinomial logistic regression predicted reliable changes in depression by BMI, body fat (BF) and visceral adiposity (VAT). Multiplicative interaction terms tested modification by sex and ethnicity. Participants with increases in body composition were less likely to experience improvements in depression (BMI: RRR = 0.79 (0.68–0.91), p < 0.01; BF: RRR = 0.97 (0.94 - 0.99), p = 0.01; VAT: RRR = 0.99 (0.98–1.00), p = 0.02), but not worsening of depression (BMI: RRR = 1.29 (0.96–1.73), p = 0.10; BF: RRR = 1.04 (0.99–1.09), p = 0.15; VAT: RRR = 1.01 (1.00–1.03), p = 0.18). Sex and ethnicity interaction terms were not significant. However, the relationship was only significant among females, among non-Latinos for BMI and BF, and among Latinos for VAT. Our study supports the association between depression and obesity and highlights the need for longitudinal studies investigating VAT and depression in diverse ethnic groups.
AB - We investigated associations between changes in depression and body composition over a 12-month weight loss trial. Of the 298 adults (BMI > 27 m/kg2), 219 with complete depression and body composition data were included. A 10-item Center for Epidemiologic Studies Depression Scale measured depression; dual-energy X-ray absorptiometry measured body composition. Multinomial logistic regression predicted reliable changes in depression by BMI, body fat (BF) and visceral adiposity (VAT). Multiplicative interaction terms tested modification by sex and ethnicity. Participants with increases in body composition were less likely to experience improvements in depression (BMI: RRR = 0.79 (0.68–0.91), p < 0.01; BF: RRR = 0.97 (0.94 - 0.99), p = 0.01; VAT: RRR = 0.99 (0.98–1.00), p = 0.02), but not worsening of depression (BMI: RRR = 1.29 (0.96–1.73), p = 0.10; BF: RRR = 1.04 (0.99–1.09), p = 0.15; VAT: RRR = 1.01 (1.00–1.03), p = 0.18). Sex and ethnicity interaction terms were not significant. However, the relationship was only significant among females, among non-Latinos for BMI and BF, and among Latinos for VAT. Our study supports the association between depression and obesity and highlights the need for longitudinal studies investigating VAT and depression in diverse ethnic groups.
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U2 - 10.1038/s41366-018-0272-1
DO - 10.1038/s41366-018-0272-1
M3 - Article
C2 - 30538278
AN - SCOPUS:85058213124
SN - 0307-0565
VL - 43
SP - 1859
EP - 1862
JO - International Journal of Obesity
JF - International Journal of Obesity
IS - 9
ER -