Associative learning impairments in patients with frontal lobe damage

Mariana Dimitrov, Joy Granetz, Matthew Peterson, Caroline Hollnagel, Gene Alexander, Jordan Grafman*

*Corresponding author for this work

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

The performance of 18 frontal lobe lesion (FL) and 10 frontal lobe dementia (FLD) patients on an associative memory test was compared with the performance of their matched normal controls. The FL group was severely impaired on cued and free recall and was moderately impaired on a recognition condition. Left FL patients performed the poorest on the cued and free recall conditions. The FLD patients were moderately impaired on the free recall condition only but there was a subgroup of FLD patients with additional left temporal atrophy who appeared severely impaired on both cued and free recall. These findings indicate that both left frontal and temporal lobe damage can impair associative learning and that this impairment is more strikingly seen with free rather than cued recall.

Original languageEnglish (US)
Pages (from-to)213-230
Number of pages18
JournalBrain and Cognition
Volume41
Issue number2
DOIs
StatePublished - Jan 1 1999

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Frontal Lobe
Learning
Dementia
Temporal Lobe
Damage
Impairment
Associative Learning
Atrophy
Cued Recall
Free Recall
Lesion

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Experimental and Cognitive Psychology
  • Developmental and Educational Psychology
  • Arts and Humanities (miscellaneous)
  • Cognitive Neuroscience

Cite this

Dimitrov, M., Granetz, J., Peterson, M., Hollnagel, C., Alexander, G., & Grafman, J. (1999). Associative learning impairments in patients with frontal lobe damage. Brain and Cognition, 41(2), 213-230. https://doi.org/10.1006/brcg.1999.1121
Dimitrov, Mariana ; Granetz, Joy ; Peterson, Matthew ; Hollnagel, Caroline ; Alexander, Gene ; Grafman, Jordan. / Associative learning impairments in patients with frontal lobe damage. In: Brain and Cognition. 1999 ; Vol. 41, No. 2. pp. 213-230.
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Dimitrov, M, Granetz, J, Peterson, M, Hollnagel, C, Alexander, G & Grafman, J 1999, 'Associative learning impairments in patients with frontal lobe damage', Brain and Cognition, vol. 41, no. 2, pp. 213-230. https://doi.org/10.1006/brcg.1999.1121

Associative learning impairments in patients with frontal lobe damage. / Dimitrov, Mariana; Granetz, Joy; Peterson, Matthew; Hollnagel, Caroline; Alexander, Gene; Grafman, Jordan.

In: Brain and Cognition, Vol. 41, No. 2, 01.01.1999, p. 213-230.

Research output: Contribution to journalArticle

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