TY - JOUR
T1 - Asymmetry of Systolic Anterior Motion of the Mitral Valve in Patients with Hypertrophic Obstructive Cardiomyopathy
T2 - A Real-time Three-dimensional Echocardiographic Study
AU - Song, Jong Min
AU - Fukuda, Shota
AU - Lever, Harry M.
AU - Daimon, Masao
AU - Agler, Deborah A.
AU - Smedira, Nicholas G.
AU - Thomas, James D.
AU - Shiota, Takahiro
PY - 2006/9
Y1 - 2006/9
N2 - By geometric analysis of real-time 3-dimensional echocardiography performed in 39 patients with hypertrophic obstructive cardiomyopathy and definite systolic anterior motion of the mitral valve, we found that the angle between the mitral annular plane and basal portion of the anterior mitral valve leaflet, and the angle between the basal portion of the anterior leaflet and its tip portion measured in the medial and central anteroposterior planes, were significantly smaller than those in the lateral plane. The distance between the interventricular septum and the anterior mitral valve tip in the medial and central plane was also significantly smaller than that in the lateral plane. The lateral distance between the interventricular septum and the anterior mitral valve tip was the only independent determinant of left ventricular outflow tract pressure gradient by multiple stepwise regression analysis. In conclusion, systolic anterior motion of the mitral valve develops predominantly in the medial side, resulting in laterally located narrow left ventricular outflow tract opening in patients with hypertrophic obstructive cardiomyopathy.
AB - By geometric analysis of real-time 3-dimensional echocardiography performed in 39 patients with hypertrophic obstructive cardiomyopathy and definite systolic anterior motion of the mitral valve, we found that the angle between the mitral annular plane and basal portion of the anterior mitral valve leaflet, and the angle between the basal portion of the anterior leaflet and its tip portion measured in the medial and central anteroposterior planes, were significantly smaller than those in the lateral plane. The distance between the interventricular septum and the anterior mitral valve tip in the medial and central plane was also significantly smaller than that in the lateral plane. The lateral distance between the interventricular septum and the anterior mitral valve tip was the only independent determinant of left ventricular outflow tract pressure gradient by multiple stepwise regression analysis. In conclusion, systolic anterior motion of the mitral valve develops predominantly in the medial side, resulting in laterally located narrow left ventricular outflow tract opening in patients with hypertrophic obstructive cardiomyopathy.
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U2 - 10.1016/j.echo.2006.04.017
DO - 10.1016/j.echo.2006.04.017
M3 - Article
C2 - 16950467
AN - SCOPUS:33748081984
SN - 0894-7317
VL - 19
SP - 1129
EP - 1135
JO - Journal of the American Society of Echocardiography
JF - Journal of the American Society of Echocardiography
IS - 9
ER -