Ataxia

Jennifer G Goldman*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The ataxias represent a diverse group of neurological disorders that affect coordination, balance, and control of movement. The ataxias discussed in this article reflect primarily cerebellar dysfunction and degeneration. There are many different etiologies for cerebellar ataxia, including sporadic disorders and hereditary ataxias. Symptoms generally involve deficits in arm and leg coordination, gait and balance, speech, swallowing, and eye movements. Although there have been tremendous advances in understanding the genetics and pathogenesis of the ataxias, improved therapeutics and disease-modifying treatments are needed.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Movement Disorders
PublisherElsevier Inc
Pages70-86
Number of pages17
ISBN (Electronic)9780123741059
ISBN (Print)9780123741011
DOIs
StatePublished - Jan 1 2010

Keywords

  • Ataxia
  • Friedreich's ataxia
  • Genetics
  • Multiple system atrophy
  • Spinocerebellar ataxias

ASJC Scopus subject areas

  • Medicine(all)
  • Neuroscience(all)

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