Blood taken from 42 patients with fever of unknown origin, including 6 patients with clinical diagnosis of 'abacteremic endocarditis' and 14 patients with microbial endocarditis, was cultured for wall defective microbial variants. No wall defective microbial variant was isolated, but classic microbial forms were repeatedly isolated in hypertonic media from 3 patients with proven endocarditis, while simultaneous cultures in routine media were sterile. No wall defective microbial variant was isolated from bone specimens obtained from 9 patients with chronic osteomyelitis. Routine cultures for wall defective microbial variants are unwarranted.
ASJC Scopus subject areas
- Pathology and Forensic Medicine