Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma: What Is It?

Melissa E. Hogg, Jeffrey D. Wayne*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations

Abstract

Liposarcoma (LPS) is the most common soft tissue sarcoma, frequently found in the thigh and retroperitoneum. LPS is commonly classified into well-differentiated LPS and dedifferentiated LPS. Histologic subtype, tumor location, and completeness of surgical resection are important prognostic indicators for LPS. Magnetic resonance imaging best characterizes extremity lesions, whereas computed tomography is most often used for intra-abdominal and retroperitoneal tumors. Surgical resection is the mainstay of treatment. Adjuvant radiation is considered for close margins. Survival for extremity tumors is favorable. However, difficulty in obtaining wide margins in the retroperitoneum predisposes to local recurrence and, ultimately, death from unresectable disease.

Original languageEnglish (US)
Pages (from-to)333-340
Number of pages8
JournalSurgical Oncology Clinics of North America
Volume21
Issue number2
DOIs
StatePublished - Apr 1 2012

Keywords

  • Atypical lipomatous tumor
  • Liposarcoma
  • Sarcoma

ASJC Scopus subject areas

  • Surgery
  • Oncology

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