This report presents a series of two patients having giant congenital nevi (400 to 650 cm 2) treated by excision and grafting with autologous cultured skin substitutes prepared from less than 20 cm 2 of donor skin autograft. Nevi were excised to fascia and grafted with cadaveric allograft for 1 week, followed by removal of the allograft and grafting with cultured skin substitutes. The mean ratio of closed to donor areas was 26. In comparison to sheet split-thickness skin grafting, cultured skin substitutes exhibited comparable cosmesis, pliability, and durability while reducing the donor-site area by approximately one order of magnitude.
|Original language||English (US)|
|Number of pages||6|
|Journal||Plastic and reconstructive surgery|
|State||Published - Nov 2004|
ASJC Scopus subject areas