Autologous cultured skin substitutes conserve donor autograft in elective treatment of congenital giant melanocytic nevus

David Passaretti, David Billmire, Richard Kagan, Julia Corcoran, Steven Boyce

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

This report presents a series of two patients having giant congenital nevi (400 to 650 cm 2) treated by excision and grafting with autologous cultured skin substitutes prepared from less than 20 cm 2 of donor skin autograft. Nevi were excised to fascia and grafted with cadaveric allograft for 1 week, followed by removal of the allograft and grafting with cultured skin substitutes. The mean ratio of closed to donor areas was 26. In comparison to sheet split-thickness skin grafting, cultured skin substitutes exhibited comparable cosmesis, pliability, and durability while reducing the donor-site area by approximately one order of magnitude.

Original languageEnglish (US)
Pages (from-to)1523-1528
Number of pages6
JournalPlastic and reconstructive surgery
Volume114
Issue number6
DOIs
StatePublished - Nov 2004

ASJC Scopus subject areas

  • Surgery

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