Automated deviation and modoling of the pressure-geometry relationship of esophageal body in impedance planimetry studies

Zhiyue Lin, Yinglian Xiao, Ikuo Hirano, Peter J. Kahrilas, John E. Pandolfino

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This study aimed to develop an automated method to investigate the pressure-geometry relationship of esophageal body in patients with eosinophilic esophagitis (EoE). Esophageal cross-sectional areas (CSAs) and intrabag pressure data were measured in 25 EoE patients with a functional luminal imaging probe (FLIP) and analyzed by a manual reading and by a customized MATLAB program with three functions: minimizing artifacts with a median filter; isolating contraction waves with a nonlinear pulse detector and deriving median values of a minimal pressure segment and corresponding narrowest esophageal CSAs during each distension; and modeling the distensibility of the esophageal body with a polynomial regression technique to derive the distension slope and distension plateau. This regression technique was also applied to manual readings for comparison. Such comparison shows that results of automated method highly correlated with manual reading (R≥0.84) and offered advantages in minimizing the influence of artifacts and inter-observer variability.

Original languageEnglish (US)
Title of host publication2014 IEEE China Summit and International Conference on Signal and Information Processing, IEEE ChinaSIP 2014 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages592-596
Number of pages5
ISBN (Electronic)9781479954032
DOIs
StatePublished - Sep 3 2014
Event2nd IEEE China Summit and International Conference on Signal and Information Processing, IEEE ChinaSIP 2014 - Xi'an, China
Duration: Jul 9 2014Jul 13 2014

Publication series

Name2014 IEEE China Summit and International Conference on Signal and Information Processing, IEEE ChinaSIP 2014 - Proceedings

Other

Other2nd IEEE China Summit and International Conference on Signal and Information Processing, IEEE ChinaSIP 2014
Country/TerritoryChina
CityXi'an
Period7/9/147/13/14

Keywords

  • Eosinophilic esophagitis
  • esophageal distensibility
  • impedance planimetry
  • median filter
  • polynomial regression

ASJC Scopus subject areas

  • Information Systems
  • Signal Processing

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