Automated microscopy system for peripheral blood cells

Sergei F. Boev, Vladimir V. Sazonov, Gennadii I. Kozinets, Valerii M. Pogorelov, Aleksandr A. Gusev, Farida V. Korobova, Aleksandr G. Vinogradov, Nataliya V. Verdenskaya, Irina A. Ivanova

Research output: Contribution to journalArticlepeer-review

Abstract

The report describes the instrument ASPBS (Automated Screening of Peripheral Blood Cells) designed for an automated analysis of dry blood smears. The instrument is based on computer microscopy and uses dry blood smears prepared according to the standard Romanovskii-Giemza procedure. In comparison with the well-known flow cytometry systems, our instrument provides more detailed information and offers an opportunity of visualizing final results. The basic performances of the instrument are given. Software of this instrument is based on digital image processing and image recognition procedures. It is pointed out that the instrument can be used as a fairly universal tool in scientific research, public demonstrations, in medical treatment, and in medical education. The principle used as the basis of the instrument appeared adequate for creating an instrument version serviceable even during space flights where standard manual procedures and flow cytometry systems fail. The benefit of the use of the instrument in clinical laboratories is described.

Original languageEnglish (US)
Pages (from-to)99-104
Number of pages6
JournalProceedings of SPIE-The International Society for Optical Engineering
Volume4163
DOIs
StatePublished - Jan 1 2000

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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