Automatic calculation of the arterial input function for cerebral perfusion imaging with MR imaging

Timothy J. Carroll*, Howard A. Rowley, Victor M. Haughton

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

101 Scopus citations

Abstract

An automated method for determination of arterial input function (AIF) for rapid determination of cerebral perfusion with dynamic susceptibility contrast magnetic resonance (MR) imaging was derived. In 100 patients, the automated method was used to create images of relative blood flow, relative cerebral blood volume, and mean transit time. In 20 patients, the voxel chosen with the automated AIF correlated with a large cerebral artery and exhibited less partial-volume averaging when compared with an AIF chosen manually. It is possible to reliably determine the AIF at dynamic susceptibility contrast MR imaging and eliminate the need for operator input and lengthy postprocessing.

Original languageEnglish (US)
Pages (from-to)593-600
Number of pages8
JournalRadiology
Volume227
Issue number2
DOIs
StatePublished - May 1 2003

Keywords

  • Brain, infarction
  • Cerebral blood vessels, flow dynamics
  • Magnetic resonance (MR), contrast enhancement
  • Magnetic resonance (MR), diffusion study
  • Magnetic resonance, vascular studies

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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