TY - JOUR
T1 - Automatic Memory Processes in Patients With Multiple Sclerosis
AU - Grafman, Jordan
AU - Rao, Stephen
AU - Bernardin, Linda
AU - Leo, Gary J.
PY - 1991/10
Y1 - 1991/10
N2 - To better understand the nature of the memory deficit in patients with multiple sclerosis, we designed a study to compare automatic vs effortful memory processes. Fortyone patients with definite multiple sclerosis and 45 demographically matched normal control subjects were administered two tasks designed to assess both automatic (monitoring frequency and modality) and effortful (free and cued-recall) processing. Results indicated that patients with multiple sclerosis, as expected, were significantly impaired on memory measures requiring effort, but performed normally on automatic measures. Performance on the memory indexes did not correlate with self-reported depression. The implications of these findings for delineating the locus of the memory impairment in multiple sclerosis is discussed.
AB - To better understand the nature of the memory deficit in patients with multiple sclerosis, we designed a study to compare automatic vs effortful memory processes. Fortyone patients with definite multiple sclerosis and 45 demographically matched normal control subjects were administered two tasks designed to assess both automatic (monitoring frequency and modality) and effortful (free and cued-recall) processing. Results indicated that patients with multiple sclerosis, as expected, were significantly impaired on memory measures requiring effort, but performed normally on automatic measures. Performance on the memory indexes did not correlate with self-reported depression. The implications of these findings for delineating the locus of the memory impairment in multiple sclerosis is discussed.
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U2 - 10.1001/archneur.1991.00530220094025
DO - 10.1001/archneur.1991.00530220094025
M3 - Article
C2 - 1929900
AN - SCOPUS:0025936141
SN - 0003-9942
VL - 48
SP - 1072
EP - 1075
JO - Archives of Neurology
JF - Archives of Neurology
IS - 10
ER -