Autophagy, Apoptosis, and the Influenza Virus M2 Protein

Jeremy S. Rossman; Robert A. Lamb

doi:10.1016/j.chom.2009.09.009

Autophagy, Apoptosis, and the Influenza Virus M2 Protein

Jeremy S. Rossman, Robert A. Lamb^*

^*Corresponding author for this work

Molecular Biosciences

Research output: Contribution to journal › Short survey › peer-review

58 Scopus citations

Abstract

Viral subversion and inhibition of host cell autophagy has been documented for several viruses. In this issue of Cell Host & Microbe, Gannagé et al. (2009) show that the influenza virus M2 integral membrane protein blocks autophagosome maturation, significantly affecting host cell apoptosis.

Original language	English (US)
Pages (from-to)	299-300
Number of pages	2
Journal	Cell Host and Microbe
Volume	6
Issue number	4
DOIs	https://doi.org/10.1016/j.chom.2009.09.009
State	Published - Nov 22 2009

ASJC Scopus subject areas

Parasitology
Microbiology
Virology

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10.1016/j.chom.2009.09.009

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title = "Autophagy, Apoptosis, and the Influenza Virus M2 Protein",

abstract = "Viral subversion and inhibition of host cell autophagy has been documented for several viruses. In this issue of Cell Host & Microbe, Gannag{\'e} et al. (2009) show that the influenza virus M2 integral membrane protein blocks autophagosome maturation, significantly affecting host cell apoptosis.",

author = "Rossman, {Jeremy S.} and Lamb, {Robert A.}",

note = "Funding Information: Work in our laboratory is supported by research grant R01 AI-20201 (R.A.L.) from the National Institutes of Allergy and Infectious Diseases. R.A.L. is an Investigator of the Howard Hughes Medical Institute.",

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AU - Rossman, Jeremy S.

AU - Lamb, Robert A.

N1 - Funding Information: Work in our laboratory is supported by research grant R01 AI-20201 (R.A.L.) from the National Institutes of Allergy and Infectious Diseases. R.A.L. is an Investigator of the Howard Hughes Medical Institute.

PY - 2009/11/22

Y1 - 2009/11/22

N2 - Viral subversion and inhibition of host cell autophagy has been documented for several viruses. In this issue of Cell Host & Microbe, Gannagé et al. (2009) show that the influenza virus M2 integral membrane protein blocks autophagosome maturation, significantly affecting host cell apoptosis.

AB - Viral subversion and inhibition of host cell autophagy has been documented for several viruses. In this issue of Cell Host & Microbe, Gannagé et al. (2009) show that the influenza virus M2 integral membrane protein blocks autophagosome maturation, significantly affecting host cell apoptosis.

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Autophagy, Apoptosis, and the Influenza Virus M2 Protein

Abstract

ASJC Scopus subject areas

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