Avascular Necrosis of the Hips With Increased Activity on 68Ga-DOTATATE PET/CT

Georgios Z. Papadakis, Corina Millo, Apostolos H. Karantanas, Ulas Bagci, Nicholas J. Patronas

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Prolonged exposure to cortisol is one of the major causes of avascular bone necrosis (AVN). We report on a case of a woman with Cushing syndrome attributed to ectopic adrenocorticotropic hormone-secreting tumor who was evaluated with whole-body PET/CT study using Ga-DOTATATE. The scan showed increased activity by both femoral heads, corresponding to the margins of bilateral AVN seen on MRI. The presented data suggests AVN-induced reactive inflammatory alterations adjacent to the necrotic segment of the bone, which can be effectively targeted using radiolabeled somatostatin (SST) analogs.

Original languageEnglish (US)
Pages (from-to)214-215
Number of pages2
JournalClinical nuclear medicine
Volume42
Issue number3
DOIs
StatePublished - Mar 1 2017
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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