B-Cell Abnormalities in AIDS

Chester W. Lerner, Carl B. Wallemark, Joan Sander Chmiel, Michael S. Gottlieb, Etty Benveniste, H. Clifford Lane, Alain H. Rook, Lynn C. Edgar, Henry Masur, Gail Whalen, Anthony S. Fauci

Research output: Contribution to journalLetter

3 Scopus citations


To the Editor: The article by Lane et al. in the August 25 issue1 enlarges the spectrum of immune dysfunction in the acquired immunodeficiency syndrome (AIDS). I question, though, the diagnosis of AIDS in 4 of their 12 patients (Patients 1, 3, 5, and 9). With no known etiologic agent or diagnostic test for AIDS, the Centers for Disease Control (CDC) case definition for surveillance2 is the accepted working criterion for AIDS and is cited by Lane et al. Although the CDC definition is subject to modification, given the public and medical concern about AIDS it seems prudent that researchers.

Original languageEnglish (US)
Pages (from-to)258-259
Number of pages2
JournalNew England Journal of Medicine
Issue number4
StatePublished - Jan 26 1984


ASJC Scopus subject areas

  • Medicine(all)

Cite this

Lerner, C. W., Wallemark, C. B., Chmiel, J. S., Gottlieb, M. S., Benveniste, E., Lane, H. C., Rook, A. H., Edgar, L. C., Masur, H., Whalen, G., & Fauci, A. S. (1984). B-Cell Abnormalities in AIDS. New England Journal of Medicine, 310(4), 258-259. https://doi.org/10.1056/NEJM198401263100411