B cell-rich non-neoplastic sentinel lesion preceding primary central nervous system lymphoma

Rodrigo Javier, Nawal Shaikh, Maciej S. Lesniak, Adam Sonabend, Roger Stupp, Amir Behdad, Craig Horbinski*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Background: Primary central nervous system lymphoma (PCNSL) is an uncommon tumor in the brain. Although most PCNSL are readily diagnosed as diffuse large B cell lymphoma (DLBCL) on the first biopsy, very rare cases have been described in which the first detected intracerebral lesions are non-neoplastic, and are composed mostly of perivascular T cells, not B cells. This phenomenon is known as "sentinel lesions."

Original languageEnglish (US)
Article number37
JournalDiagnostic pathology
Volume13
Issue number1
DOIs
StatePublished - Jun 5 2018

Keywords

  • Diffuse large B cell lymphoma
  • Primary CNS lymphoma
  • Sentinel lesion

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

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