To colonize during disease and prevent consumption by environmental unicellular eukaryotes, bacteria often disrupt phagocytosis. In this issue, Ma et al. (2009) show that Vibrio cholerae delivers the actin-crosslinking T6SS effector VgrG-1 following phagocytosis. The effector then causes irreversible cytoskeleton destruction, leading to bystander protection of the extracellular bacterial population.
ASJC Scopus subject areas
- Immunology and Microbiology(all)
- Cancer Research
- Molecular Biology