Bacterial Martyrdom: Phagocytes Disabled by Type VI Secretion after Engulfing Bacteria

Karla J.F. Satchell*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

6 Scopus citations

Abstract

To colonize during disease and prevent consumption by environmental unicellular eukaryotes, bacteria often disrupt phagocytosis. In this issue, Ma et al. (2009) show that Vibrio cholerae delivers the actin-crosslinking T6SS effector VgrG-1 following phagocytosis. The effector then causes irreversible cytoskeleton destruction, leading to bystander protection of the extracellular bacterial population.

Original languageEnglish (US)
Pages (from-to)213-214
Number of pages2
JournalCell Host and Microbe
Volume5
Issue number3
DOIs
StatePublished - Mar 19 2009

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Virology

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