Abstract
The fluoroquinolone WIN 57273 showed identical bactericidal activities (MBC for 90% of the strains = 0.25 μg/ml) for bacteremic strains of Enterococcus faecalis with and without high-level gentamicin resistance. WIN 57273 was bactericidal in time-kill measurements with highly gentamicin- resistant, ciprofloxacin-susceptible strains of E. faecalis. However, WIN 57273 was indifferent with penicillin for gentamicin-resistant E. faecalis and was not bactericidal for ciprofloxacin-resistant E. faecalis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2470-2473 |
| Number of pages | 4 |
| Journal | Antimicrobial agents and chemotherapy |
| Volume | 37 |
| Issue number | 11 |
| DOIs |
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| State | Published - 1993 |
ASJC Scopus subject areas
- Pharmacology (medical)
- Infectious Diseases
- Pharmacology