Bartonella-related multifocal bone marrow enhancement without osteolysis

Scott V. Connelly, Patrick C. Seed

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Multifocal bone marrow disease due to Bartonella henselae is rare and is typically accompanied by osteolytic disease. A 10-year-old female presented with advanced disease, including prolonged fever, back pain, and radiographic multifocal pelvic bone marrow enhancement without osteolysis. Acute and convalescent serology supported the diagnosis of B. henselae infection. However, bone marrow aspirates lacked granulomas and inflammatory infiltrate. The patient fully recovered without specific antimicrobial therapy. B. henselae produces a fever and pain syndrome with multifocal bone marrow enhancement in the absence of osteolytic lesions.

Original languageEnglish (US)
Pages (from-to)305-308
Number of pages4
JournalJournal of Pediatric Infectious Diseases
Volume5
Issue number3
DOIs
StatePublished - Dec 24 2010

Fingerprint

Bartonella henselae
Bartonella
Osteolysis
Bone Marrow
Fever
Bone Marrow Diseases
Bartonella Infections
Pelvic Bones
Serology
Back Pain
Granuloma
Pain
Therapeutics

Keywords

  • Bartonella henselae
  • bone marrow enhancement
  • children
  • fever of unknown origin
  • osteomyelitis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Infectious Diseases

Cite this

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Bartonella-related multifocal bone marrow enhancement without osteolysis. / Connelly, Scott V.; Seed, Patrick C.

In: Journal of Pediatric Infectious Diseases, Vol. 5, No. 3, 24.12.2010, p. 305-308.

Research output: Contribution to journalArticle

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AU - Seed, Patrick C.

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AB - Multifocal bone marrow disease due to Bartonella henselae is rare and is typically accompanied by osteolytic disease. A 10-year-old female presented with advanced disease, including prolonged fever, back pain, and radiographic multifocal pelvic bone marrow enhancement without osteolysis. Acute and convalescent serology supported the diagnosis of B. henselae infection. However, bone marrow aspirates lacked granulomas and inflammatory infiltrate. The patient fully recovered without specific antimicrobial therapy. B. henselae produces a fever and pain syndrome with multifocal bone marrow enhancement in the absence of osteolytic lesions.

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