Baseline Lower Urinary Tract Symptoms in Patients Enrolled in LURN

A Prospective, Observational Cohort Study

Symptoms of Lower Urinary Tract Dysfunction Research Network Study Group

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Purpose: We described and compared the frequency and type of lower urinary tract symptoms reported by men and women at the time that they were recruited from urology and urogynecology clinics into the Symptoms of Lower Urinary Tract Dysfunction Research Network multicenter, prospective, observational cohort study. Materials and Methods: At 6 research sites treatment seeking men and women were enrolled who reported any lower urinary tract symptoms at a frequency more than rarely during the last month on the LUTS (Lower Urinary Tract Symptoms) Tool. At baseline the study participants underwent a standardized clinical evaluation and completed validated questionnaires. Urological tests were performed, including pelvic/rectal examination, post-void residual urine measurement and urinalysis. Results: A total of 545 women and 519 men were enrolled in the study. Mean ± SD age was 58.8 ± 14.1 years. At baseline nocturia, frequency and a sensation of incomplete emptying were similar in men and women but men experienced more voiding symptoms (90% vs 85%, p = 0.007) and women reported more urgency (85% vs 66%, p <0.001). Women also reported more of any type of urinary incontinence than men (82% vs 51% p <0.001), which was mixed incontinence in 57%. Only 1% of men reported stress incontinence but they had other urinary incontinence, including post-void dribbling in 44% and urgency incontinence in 46%. Older participants had higher odds of reporting symptoms of nocturia and urgency. Conclusions: In this large, treatment seeking cohort of men and women lower urinary tract symptoms varied widely by gender and age. Men reported more voiding symptoms and nonstress or urgency urinary incontinence while women reported more incontinence overall and urgency. Older participants had greater odds of urgency and nocturia.

Original languageEnglish (US)
Pages (from-to)1023-1031
Number of pages9
JournalJournal of Urology
Volume199
Issue number4
DOIs
StatePublished - Apr 1 2018

Fingerprint

Lower Urinary Tract Symptoms
Observational Studies
Cohort Studies
Nocturia
Urinary Incontinence
Gynecological Examination
Urinalysis
Urology
Research
Urine

Keywords

  • lower urinary tract symptoms
  • men's health
  • overactive
  • urinary bladder
  • urinary incontinence
  • women's health

ASJC Scopus subject areas

  • Urology

Cite this

Symptoms of Lower Urinary Tract Dysfunction Research Network Study Group. / Baseline Lower Urinary Tract Symptoms in Patients Enrolled in LURN : A Prospective, Observational Cohort Study. In: Journal of Urology. 2018 ; Vol. 199, No. 4. pp. 1023-1031.
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title = "Baseline Lower Urinary Tract Symptoms in Patients Enrolled in LURN: A Prospective, Observational Cohort Study",
abstract = "Purpose: We described and compared the frequency and type of lower urinary tract symptoms reported by men and women at the time that they were recruited from urology and urogynecology clinics into the Symptoms of Lower Urinary Tract Dysfunction Research Network multicenter, prospective, observational cohort study. Materials and Methods: At 6 research sites treatment seeking men and women were enrolled who reported any lower urinary tract symptoms at a frequency more than rarely during the last month on the LUTS (Lower Urinary Tract Symptoms) Tool. At baseline the study participants underwent a standardized clinical evaluation and completed validated questionnaires. Urological tests were performed, including pelvic/rectal examination, post-void residual urine measurement and urinalysis. Results: A total of 545 women and 519 men were enrolled in the study. Mean ± SD age was 58.8 ± 14.1 years. At baseline nocturia, frequency and a sensation of incomplete emptying were similar in men and women but men experienced more voiding symptoms (90{\%} vs 85{\%}, p = 0.007) and women reported more urgency (85{\%} vs 66{\%}, p <0.001). Women also reported more of any type of urinary incontinence than men (82{\%} vs 51{\%} p <0.001), which was mixed incontinence in 57{\%}. Only 1{\%} of men reported stress incontinence but they had other urinary incontinence, including post-void dribbling in 44{\%} and urgency incontinence in 46{\%}. Older participants had higher odds of reporting symptoms of nocturia and urgency. Conclusions: In this large, treatment seeking cohort of men and women lower urinary tract symptoms varied widely by gender and age. Men reported more voiding symptoms and nonstress or urgency urinary incontinence while women reported more incontinence overall and urgency. Older participants had greater odds of urgency and nocturia.",
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author = "{Symptoms of Lower Urinary Tract Dysfunction Research Network Study Group} and Cameron, {Anne P.} and Gaupp, {Christina Lewicky} and Smith, {Abigail R.} and Helfand, {Brian T.} and Gore, {John L.} and Clemens, {J. Quentin} and Yang, {Claire C.} and Siddiqui, {Nazema Y.} and Lai, {H. Henry} and Griffith, {James W} and Andreev, {Victor P.} and Gang Liu and Kevin Weinfurt and Amundsen, {Cindy L.} and Bradley, {Catherine S.} and Kusek, {John W.} and Ziya Kirkali",
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Symptoms of Lower Urinary Tract Dysfunction Research Network Study Group 2018, 'Baseline Lower Urinary Tract Symptoms in Patients Enrolled in LURN: A Prospective, Observational Cohort Study', Journal of Urology, vol. 199, no. 4, pp. 1023-1031. https://doi.org/10.1016/j.juro.2017.10.035

Baseline Lower Urinary Tract Symptoms in Patients Enrolled in LURN : A Prospective, Observational Cohort Study. / Symptoms of Lower Urinary Tract Dysfunction Research Network Study Group.

In: Journal of Urology, Vol. 199, No. 4, 01.04.2018, p. 1023-1031.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Baseline Lower Urinary Tract Symptoms in Patients Enrolled in LURN

T2 - A Prospective, Observational Cohort Study

AU - Symptoms of Lower Urinary Tract Dysfunction Research Network Study Group

AU - Cameron, Anne P.

AU - Gaupp, Christina Lewicky

AU - Smith, Abigail R.

AU - Helfand, Brian T.

AU - Gore, John L.

AU - Clemens, J. Quentin

AU - Yang, Claire C.

AU - Siddiqui, Nazema Y.

AU - Lai, H. Henry

AU - Griffith, James W

AU - Andreev, Victor P.

AU - Liu, Gang

AU - Weinfurt, Kevin

AU - Amundsen, Cindy L.

AU - Bradley, Catherine S.

AU - Kusek, John W.

AU - Kirkali, Ziya

PY - 2018/4/1

Y1 - 2018/4/1

N2 - Purpose: We described and compared the frequency and type of lower urinary tract symptoms reported by men and women at the time that they were recruited from urology and urogynecology clinics into the Symptoms of Lower Urinary Tract Dysfunction Research Network multicenter, prospective, observational cohort study. Materials and Methods: At 6 research sites treatment seeking men and women were enrolled who reported any lower urinary tract symptoms at a frequency more than rarely during the last month on the LUTS (Lower Urinary Tract Symptoms) Tool. At baseline the study participants underwent a standardized clinical evaluation and completed validated questionnaires. Urological tests were performed, including pelvic/rectal examination, post-void residual urine measurement and urinalysis. Results: A total of 545 women and 519 men were enrolled in the study. Mean ± SD age was 58.8 ± 14.1 years. At baseline nocturia, frequency and a sensation of incomplete emptying were similar in men and women but men experienced more voiding symptoms (90% vs 85%, p = 0.007) and women reported more urgency (85% vs 66%, p <0.001). Women also reported more of any type of urinary incontinence than men (82% vs 51% p <0.001), which was mixed incontinence in 57%. Only 1% of men reported stress incontinence but they had other urinary incontinence, including post-void dribbling in 44% and urgency incontinence in 46%. Older participants had higher odds of reporting symptoms of nocturia and urgency. Conclusions: In this large, treatment seeking cohort of men and women lower urinary tract symptoms varied widely by gender and age. Men reported more voiding symptoms and nonstress or urgency urinary incontinence while women reported more incontinence overall and urgency. Older participants had greater odds of urgency and nocturia.

AB - Purpose: We described and compared the frequency and type of lower urinary tract symptoms reported by men and women at the time that they were recruited from urology and urogynecology clinics into the Symptoms of Lower Urinary Tract Dysfunction Research Network multicenter, prospective, observational cohort study. Materials and Methods: At 6 research sites treatment seeking men and women were enrolled who reported any lower urinary tract symptoms at a frequency more than rarely during the last month on the LUTS (Lower Urinary Tract Symptoms) Tool. At baseline the study participants underwent a standardized clinical evaluation and completed validated questionnaires. Urological tests were performed, including pelvic/rectal examination, post-void residual urine measurement and urinalysis. Results: A total of 545 women and 519 men were enrolled in the study. Mean ± SD age was 58.8 ± 14.1 years. At baseline nocturia, frequency and a sensation of incomplete emptying were similar in men and women but men experienced more voiding symptoms (90% vs 85%, p = 0.007) and women reported more urgency (85% vs 66%, p <0.001). Women also reported more of any type of urinary incontinence than men (82% vs 51% p <0.001), which was mixed incontinence in 57%. Only 1% of men reported stress incontinence but they had other urinary incontinence, including post-void dribbling in 44% and urgency incontinence in 46%. Older participants had higher odds of reporting symptoms of nocturia and urgency. Conclusions: In this large, treatment seeking cohort of men and women lower urinary tract symptoms varied widely by gender and age. Men reported more voiding symptoms and nonstress or urgency urinary incontinence while women reported more incontinence overall and urgency. Older participants had greater odds of urgency and nocturia.

KW - lower urinary tract symptoms

KW - men's health

KW - overactive

KW - urinary bladder

KW - urinary incontinence

KW - women's health

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