Basic science of bone fusion

Joseph A. Weiner*, Wellington K. Hsu

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter


Spine arthrodesis is frequently performed in the treatment of spine trauma, deformity, and degenerative disorders. With an estimated 413,000 fusion procedures performed in the United States annually, the number of procedures performed has increased by 2.4-fold since 1998. Based on its prevalence, it is critical that spine surgeons have an adequate understanding of the basic science behind bone fusion. This chapter will review basic bone anatomy and histology, discuss the principles and process of bone healing, and explore the clinical applications of these topics.

Original languageEnglish (US)
Title of host publicationEssentials of Spinal Stabilization
PublisherSpringer International Publishing
Number of pages15
ISBN (Electronic)9783319597133
ISBN (Print)9783319597126
StatePublished - Jan 1 2017


  • Bone fusion
  • Bone healing
  • Bone metabolism
  • Cigarette smoke
  • Nutrition
  • Regeneration
  • Regulation
  • Vitamin D

ASJC Scopus subject areas

  • Medicine(all)

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