Basophils are elevated in nasal polyps of patients with chronic rhinosinusitis without aspirin sensitivity

Mahboobeh Mahdavinia; Roderick G. Carter; Christopher J. Ocampo; Whitney Stevens; Atsushi Kato; Bruce K. Tan; Robert C. Kern; David B. Conley; Rakesh Chandra; Kathryn E. Hulse; Lydia A. Suh; James E. Norton; Anju T. Peters; Leslie C. Grammer; Lawrence B. Schwartz; Robert P. Schleimer

doi:10.1016/j.jaci.2013.12.1092

Basophils are elevated in nasal polyps of patients with chronic rhinosinusitis without aspirin sensitivity

Mahboobeh Mahdavinia, Roderick G. Carter, Christopher J. Ocampo, Whitney Stevens, Atsushi Kato, Bruce K. Tan, Robert C. Kern, David B. Conley, Rakesh Chandra, Kathryn E. Hulse, Lydia A. Suh, James E. Norton, Anju T. Peters, Leslie C. Grammer, Lawrence B. Schwartz, Robert P. Schleimer

Research output: Contribution to journal › Article › peer-review

83 Scopus citations

Original language	English (US)
Pages (from-to)	1759-1763
Number of pages	5
Journal	Journal of Allergy and Clinical Immunology
Volume	133
Issue number	6
DOIs	https://doi.org/10.1016/j.jaci.2013.12.1092
State	Published - Jun 2014

Funding

This study was supported by the National Institutes of Health (grants R37 HL068546 , R01 HL078860 , R01 AI072570 , and R21 HL113913 ) and the Ernest S. Bazley Trust . Disclosure of potential conflict of interest: A. Kato has received research support from the National Institutes of Health (NIH) . B. K. Tan has received research support from the NIH and the Trilogical Society-American College of Surgeons ; has consultant arrangements with Acclarent, Inc; and has received travel support from the Foundation for Innovation, Education, and Research in Otorhinolaryngology. A. T. Peters has received payment for lectures from Baxter. L. C. Grammer has received research support from the NIH , the Food Allergy Network , and S&C Electric ; has received travel support from the NIH ; has received a grant from the Bazley Foundation ; has consultant arrangements from Astellas Pharmaceuticals; is employed by Northwestern University and Northwestern Medical Faculty Foundation; has received payment for lectures from the American Academy of Allergy, Asthma & Immunology and Mount Sinai; and has received royalties from Lippincott, UpToDate, BMJ, and Elsevier. L. B. Schwartz is a member of the Board of Directors for the Clinical Immunology Society and the Asthma and Allergy Foundation of America; has consultant arrangements with Sanofi Aventis, Dyax, and ViroPharma; has received research support from CSL Behring , Dyax , and the Mastocytosis Society/MastoKids ; has received royalties for licensing arrangements for tryptase assay, antitryptase and antichymase mAbs, and anti-basophil mAb from VCU Tech Transfer; and is associate editor of the Journal of Clinical Immunology. R. P. Schleimer has received research support from the NIH ; has consultant arrangements with Intersect ENT, GlaxoSmithKline, Allakos, Aurasense, Merck, and BioMarck; and has stock/stock options in Allakos and Aurasense. The rest of the authors declare that they have no relevant conflicts of interest.

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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Mahdavinia, M., Carter, R. G., Ocampo, C. J., Stevens, W., Kato, A., Tan, B. K., Kern, R. C., Conley, D. B., Chandra, R., Hulse, K. E., Suh, L. A., Norton, J. E., Peters, A. T., Grammer, L. C., Schwartz, L. B., & Schleimer, R. P. (2014). Basophils are elevated in nasal polyps of patients with chronic rhinosinusitis without aspirin sensitivity. Journal of Allergy and Clinical Immunology, 133(6), 1759-1763. https://doi.org/10.1016/j.jaci.2013.12.1092

@article{87f3a072b06544b49be0e913594e1c67,

title = "Basophils are elevated in nasal polyps of patients with chronic rhinosinusitis without aspirin sensitivity",

author = "Mahboobeh Mahdavinia and Carter, {Roderick G.} and Ocampo, {Christopher J.} and Whitney Stevens and Atsushi Kato and Tan, {Bruce K.} and Kern, {Robert C.} and Conley, {David B.} and Rakesh Chandra and Hulse, {Kathryn E.} and Suh, {Lydia A.} and Norton, {James E.} and Peters, {Anju T.} and Grammer, {Leslie C.} and Schwartz, {Lawrence B.} and Schleimer, {Robert P.}",

note = "Funding Information: This study was supported by the National Institutes of Health (grants R37 HL068546 , R01 HL078860 , R01 AI072570 , and R21 HL113913 ) and the Ernest S. Bazley Trust . Funding Information: Disclosure of potential conflict of interest: A. Kato has received research support from the National Institutes of Health (NIH) . B. K. Tan has received research support from the NIH and the Trilogical Society-American College of Surgeons ; has consultant arrangements with Acclarent, Inc; and has received travel support from the Foundation for Innovation, Education, and Research in Otorhinolaryngology. A. T. Peters has received payment for lectures from Baxter. L. C. Grammer has received research support from the NIH , the Food Allergy Network , and S&C Electric ; has received travel support from the NIH ; has received a grant from the Bazley Foundation ; has consultant arrangements from Astellas Pharmaceuticals; is employed by Northwestern University and Northwestern Medical Faculty Foundation; has received payment for lectures from the American Academy of Allergy, Asthma & Immunology and Mount Sinai; and has received royalties from Lippincott, UpToDate, BMJ, and Elsevier. L. B. Schwartz is a member of the Board of Directors for the Clinical Immunology Society and the Asthma and Allergy Foundation of America; has consultant arrangements with Sanofi Aventis, Dyax, and ViroPharma; has received research support from CSL Behring , Dyax , and the Mastocytosis Society/MastoKids ; has received royalties for licensing arrangements for tryptase assay, antitryptase and antichymase mAbs, and anti-basophil mAb from VCU Tech Transfer; and is associate editor of the Journal of Clinical Immunology. R. P. Schleimer has received research support from the NIH ; has consultant arrangements with Intersect ENT, GlaxoSmithKline, Allakos, Aurasense, Merck, and BioMarck; and has stock/stock options in Allakos and Aurasense. The rest of the authors declare that they have no relevant conflicts of interest. ",

year = "2014",

month = jun,

doi = "10.1016/j.jaci.2013.12.1092",

language = "English (US)",

volume = "133",

pages = "1759--1763",

journal = "Journal of Allergy and Clinical Immunology",

issn = "0091-6749",

publisher = "Mosby Inc.",

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}

Mahdavinia, M, Carter, RG, Ocampo, CJ, Stevens, W , Kato, A , Tan, BK , Kern, RC , Conley, DB, Chandra, R, Hulse, KE, Suh, LA, Norton, JE, Peters, AT , Grammer, LC, Schwartz, LB & Schleimer, RP 2014, 'Basophils are elevated in nasal polyps of patients with chronic rhinosinusitis without aspirin sensitivity', Journal of Allergy and Clinical Immunology, vol. 133, no. 6, pp. 1759-1763. https://doi.org/10.1016/j.jaci.2013.12.1092

TY - JOUR

T1 - Basophils are elevated in nasal polyps of patients with chronic rhinosinusitis without aspirin sensitivity

AU - Mahdavinia, Mahboobeh

AU - Carter, Roderick G.

AU - Ocampo, Christopher J.

AU - Stevens, Whitney

AU - Kato, Atsushi

AU - Tan, Bruce K.

AU - Kern, Robert C.

AU - Conley, David B.

AU - Chandra, Rakesh

AU - Hulse, Kathryn E.

AU - Suh, Lydia A.

AU - Norton, James E.

AU - Peters, Anju T.

AU - Grammer, Leslie C.

AU - Schwartz, Lawrence B.

AU - Schleimer, Robert P.

N1 - Funding Information: This study was supported by the National Institutes of Health (grants R37 HL068546 , R01 HL078860 , R01 AI072570 , and R21 HL113913 ) and the Ernest S. Bazley Trust . Funding Information: Disclosure of potential conflict of interest: A. Kato has received research support from the National Institutes of Health (NIH) . B. K. Tan has received research support from the NIH and the Trilogical Society-American College of Surgeons ; has consultant arrangements with Acclarent, Inc; and has received travel support from the Foundation for Innovation, Education, and Research in Otorhinolaryngology. A. T. Peters has received payment for lectures from Baxter. L. C. Grammer has received research support from the NIH , the Food Allergy Network , and S&C Electric ; has received travel support from the NIH ; has received a grant from the Bazley Foundation ; has consultant arrangements from Astellas Pharmaceuticals; is employed by Northwestern University and Northwestern Medical Faculty Foundation; has received payment for lectures from the American Academy of Allergy, Asthma & Immunology and Mount Sinai; and has received royalties from Lippincott, UpToDate, BMJ, and Elsevier. L. B. Schwartz is a member of the Board of Directors for the Clinical Immunology Society and the Asthma and Allergy Foundation of America; has consultant arrangements with Sanofi Aventis, Dyax, and ViroPharma; has received research support from CSL Behring , Dyax , and the Mastocytosis Society/MastoKids ; has received royalties for licensing arrangements for tryptase assay, antitryptase and antichymase mAbs, and anti-basophil mAb from VCU Tech Transfer; and is associate editor of the Journal of Clinical Immunology. R. P. Schleimer has received research support from the NIH ; has consultant arrangements with Intersect ENT, GlaxoSmithKline, Allakos, Aurasense, Merck, and BioMarck; and has stock/stock options in Allakos and Aurasense. The rest of the authors declare that they have no relevant conflicts of interest.

PY - 2014/6

Y1 - 2014/6

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U2 - 10.1016/j.jaci.2013.12.1092

DO - 10.1016/j.jaci.2013.12.1092

M3 - Article

C2 - 24636088

AN - SCOPUS:84901814621

SN - 0091-6749

VL - 133

SP - 1759

EP - 1763

JO - Journal of Allergy and Clinical Immunology

JF - Journal of Allergy and Clinical Immunology

IS - 6

ER -

Basophils are elevated in nasal polyps of patients with chronic rhinosinusitis without aspirin sensitivity

Funding

ASJC Scopus subject areas

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