Bayesian classification with local probabilistic model assumption in aiding medical diagnosis

Bin Hu, Chengsheng Mao, Xiaowei Zhang, Yongqiang Dai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Scopus citations

Abstract

In computer-aided diagnosis, a Bayesian classifier that can give the class membership probabilities should be more favorable than classifiers that only give a class assertion. In Bayesian classification, an important and critical step is the probability distribution estimation for each class. Existing methods usually estimate the probability distribution in the whole sample space where the original distribution may be too complex to model. In this paper, we propose a probability distribution estimation method based on local probabilistic model assumption. In our method, the estimation of global probability for a certain point is transformed to the computation of local distribution in a small region, where the local distribution is supposed to be simpler and can be assumed as a simpler probabilistic model. By this method, we implement the Bayesian classifiers based on several local probabilistic model assumptions, and experiments with these classifier have been conducted on several real-word biological and medical datasets; the experimental results demonstrate the efficacy of the proposed method for probabilistic classification in medical diagnosis.

Original languageEnglish (US)
Title of host publicationProceedings - 2015 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2015
Editorslng. Matthieu Schapranow, Jiayu Zhou, Xiaohua Tony Hu, Bin Ma, Sanguthevar Rajasekaran, Satoru Miyano, Illhoi Yoo, Brian Pierce, Amarda Shehu, Vijay K. Gombar, Brian Chen, Vinay Pai, Jun Huan
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages691-694
Number of pages4
ISBN (Electronic)9781467367981
DOIs
StatePublished - Dec 16 2015
EventIEEE International Conference on Bioinformatics and Biomedicine, BIBM 2015 - Washington, United States
Duration: Nov 9 2015Nov 12 2015

Publication series

NameProceedings - 2015 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2015

Other

OtherIEEE International Conference on Bioinformatics and Biomedicine, BIBM 2015
Country/TerritoryUnited States
CityWashington
Period11/9/1511/12/15

Funding

This work was supported by the National Basic Research Program of China (2014CB744600), the National Natural Science Foundation of China (61402211, 61063028 and 61210010) and the International Cooperation Project of Ministry of Science and Technology (20 13DFA 11 140).

Keywords

  • Bayesian classification
  • computer-aided diagnosis
  • local learning
  • probabilistic model

ASJC Scopus subject areas

  • Software
  • Artificial Intelligence
  • Health Informatics
  • Biomedical Engineering

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