Behavioral approach system (BAS) sensitivity and bipolar spectrum disorders: A retrospective and concurrent behavioral high-risk design

Lauren B. Alloy*, Lyn Y. Abramson, Patricia D. Walshaw, Alex Cogswell, Jeannette M. Smith, Amy M. Neeren, Megan E. Hughes, Brian M. Iacoviello, Rachel K. Gerstein, Jessica Keyser, Snezana Urosevic, Robin Nusslock

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

74 Scopus citations

Abstract

In this article, we tested the vulnerability hypothesis of the behavioral approach system (BAS) hypersensitivity model of bipolar disorders. We examined whether self-reported BAS sensitivity predicts lifetime bipolar spectrum diagnoses as well as symptoms and personality characteristics associated with bipolar disorder using a retrospective and concurrent behavioral high-risk design. Participants with high (HBAS; n=28) or moderate (MBAS; n=24) BAS sensitivity were selected and given a lifetime psychiatric diagnostic interview and self-report measures of proneness to bipolar symptoms, current symptoms, and personality characteristics relevant to bipolarity. HBAS participants were significantly and substantially more likely to have a lifetime bipolar spectrum disorder diagnosis than were MBAS participants, but did not differ from MBAS participants in their likelihood of a unipolar depression diagnosis. Also, the HBAS group exhibited higher impulsivity and proneness to hypomanic symptoms than the MBAS group, and BAS-reward responsiveness predicted hypomanic personality characteristics. Finally, high behavioral inhibition system (BIS) sensitivity was associated with proneness to and current depressive symptoms.

Original languageEnglish (US)
Pages (from-to)143-155
Number of pages13
JournalMotivation and Emotion
Volume30
Issue number2
DOIs
StatePublished - Jun 1 2006

Keywords

  • Behavioral approach system
  • Behavioral high-risk design
  • Behavioral inhibition system
  • Bipolar disorders
  • Depression
  • Hypomania

ASJC Scopus subject areas

  • Social Psychology
  • Experimental and Cognitive Psychology

Fingerprint Dive into the research topics of 'Behavioral approach system (BAS) sensitivity and bipolar spectrum disorders: A retrospective and concurrent behavioral high-risk design'. Together they form a unique fingerprint.

Cite this