TY - JOUR
T1 - Behavioral approach system (BAS) sensitivity and bipolar spectrum disorders
T2 - A retrospective and concurrent behavioral high-risk design
AU - Alloy, Lauren B.
AU - Abramson, Lyn Y.
AU - Walshaw, Patricia D.
AU - Cogswell, Alex
AU - Smith, Jeannette M.
AU - Neeren, Amy M.
AU - Hughes, Megan E.
AU - Iacoviello, Brian M.
AU - Gerstein, Rachel K.
AU - Keyser, Jessica
AU - Urosevic, Snezana
AU - Nusslock, Robin
PY - 2006/6/1
Y1 - 2006/6/1
N2 - In this article, we tested the vulnerability hypothesis of the behavioral approach system (BAS) hypersensitivity model of bipolar disorders. We examined whether self-reported BAS sensitivity predicts lifetime bipolar spectrum diagnoses as well as symptoms and personality characteristics associated with bipolar disorder using a retrospective and concurrent behavioral high-risk design. Participants with high (HBAS; n=28) or moderate (MBAS; n=24) BAS sensitivity were selected and given a lifetime psychiatric diagnostic interview and self-report measures of proneness to bipolar symptoms, current symptoms, and personality characteristics relevant to bipolarity. HBAS participants were significantly and substantially more likely to have a lifetime bipolar spectrum disorder diagnosis than were MBAS participants, but did not differ from MBAS participants in their likelihood of a unipolar depression diagnosis. Also, the HBAS group exhibited higher impulsivity and proneness to hypomanic symptoms than the MBAS group, and BAS-reward responsiveness predicted hypomanic personality characteristics. Finally, high behavioral inhibition system (BIS) sensitivity was associated with proneness to and current depressive symptoms.
AB - In this article, we tested the vulnerability hypothesis of the behavioral approach system (BAS) hypersensitivity model of bipolar disorders. We examined whether self-reported BAS sensitivity predicts lifetime bipolar spectrum diagnoses as well as symptoms and personality characteristics associated with bipolar disorder using a retrospective and concurrent behavioral high-risk design. Participants with high (HBAS; n=28) or moderate (MBAS; n=24) BAS sensitivity were selected and given a lifetime psychiatric diagnostic interview and self-report measures of proneness to bipolar symptoms, current symptoms, and personality characteristics relevant to bipolarity. HBAS participants were significantly and substantially more likely to have a lifetime bipolar spectrum disorder diagnosis than were MBAS participants, but did not differ from MBAS participants in their likelihood of a unipolar depression diagnosis. Also, the HBAS group exhibited higher impulsivity and proneness to hypomanic symptoms than the MBAS group, and BAS-reward responsiveness predicted hypomanic personality characteristics. Finally, high behavioral inhibition system (BIS) sensitivity was associated with proneness to and current depressive symptoms.
KW - Behavioral approach system
KW - Behavioral high-risk design
KW - Behavioral inhibition system
KW - Bipolar disorders
KW - Depression
KW - Hypomania
UR - http://www.scopus.com/inward/record.url?scp=33749593116&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33749593116&partnerID=8YFLogxK
U2 - 10.1007/s11031-006-9003-3
DO - 10.1007/s11031-006-9003-3
M3 - Article
AN - SCOPUS:33749593116
VL - 30
SP - 143
EP - 155
JO - Motivation and Emotion
JF - Motivation and Emotion
SN - 0146-7239
IS - 2
ER -