Behavioral-independent features of complex heartbeat dynamics

Luís A. Nunes Amaral, Plamen Ch Ivanov, Naoko Aoyagi, Ichiro Hidaka, Shinji Tomono, Ary L. Goldberger, H. Eugene Stanley, Yoshiharu Yamamoto

Research output: Contribution to journalArticlepeer-review

242 Scopus citations


To test the possibility that the multifractality in healthy heartbeat dynamics is related to neuroautonomic control, an attempt was made to analyze data from six subjects (four male, two female) who were administered a beta-blocking drug which reduces sympathetic control. Eight data sets from the six subjects for the second and/or third day of beta-blocker administration were analyzed. As a control, eight data sets for the same subjects but for the second and/or third day of placebo administration were also analyzed. The results indicate that when fluctuations in physical activity and other behavioral modifiers are minimized, a remarkable level of complexity of heartbeat dynamics remains, while for neuroautonomic blockade the multifractal complexity decreases.

Original languageEnglish (US)
Pages (from-to)6026-6029
Number of pages4
JournalPhysical review letters
Issue number26 I
StatePublished - Jun 25 2001

ASJC Scopus subject areas

  • General Physics and Astronomy


Dive into the research topics of 'Behavioral-independent features of complex heartbeat dynamics'. Together they form a unique fingerprint.

Cite this