Bethesda 2014: Improving on a paradigm shift

D. C. Wilbur*, R. Nayar

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


The third iteration of the Bethesda System terminology manual was recently published. This update included changes in the reporting of benign endometrial cells, and guidance for special adequacy situations and for cases in which low grade squamous intraepithelial lesions are accompanied by some cells suggesting that a high grade lesion might also be present. In addition, the manual was increased in size to include more illustrations with special studies and comparisons to histology, a greatly increased reference list, and a new chapter devoted to the modern practice of risk-based management. The third edition of the Bethesda manual is meant to serve as a primary reference for the practice of gynecologic cytology designed to provide a uniform system of reporting Worldwide for clinical, teaching, and research purposes.

Original languageEnglish (US)
Pages (from-to)339-342
Number of pages4
Issue number6
StatePublished - Dec 1 2015


  • Bethesda System
  • Gynecologic cytology
  • Pap test

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology


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