Bilateral Non-Arteritic Anterior Ischaemic Optic Neuropathy in a Patient with a COL4A2 Mutation

Kasim Qureshi, Muhammad U. Farooq*, Avneet Deol, Christopher Glisson, Philip B. Gorelick

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Non-arteritic anterior ischaemic optic neuropathy (NAION) is a common cause of vision loss in adults and is thought to be due to compromised perfusion to the optic nerve head. Patients with NAION in one eye are at risk of recurrence in the fellow eye. We report a case of sequential, bilateral NAION in a patient who was found to have a COL4A2 mutation. COL4A2 encodes a subunit of the collagen 4 protein, the major component of the human basement membranes, and has several known cerebrovascular and ocular associations.

Original languageEnglish (US)
Pages (from-to)190-193
Number of pages4
JournalNeuro-Ophthalmology
Volume46
Issue number3
DOIs
StatePublished - 2022

Keywords

  • COL4A2
  • Non-arteritic anterior ischaemic optic neuropathy
  • collagen vascular disease

ASJC Scopus subject areas

  • Clinical Neurology
  • Ophthalmology

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