Bilateral optic disc swelling following anastrozole therapy

Oscar Jim Michael Coppes; Rimas V. Lukas; Gini F. Fleming; Jeffrey Nichols; Meaghan Tenney; Jacqueline Bernard

doi:10.3109/01658107.2014.924968

Bilateral optic disc swelling following anastrozole therapy

Oscar Jim Michael Coppes^*, Rimas V. Lukas, Gini F. Fleming, Jeffrey Nichols, Meaghan Tenney, Jacqueline Bernard

^*Corresponding author for this work

Neurology

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

A 56-year-old female with early-stage breast cancer, stage IA grade 1 endometrial cancer, and stage IC grade 1 ovarian cancer developed sudden-onset visual changes and right inferior visual field defect following anastrozole therapy. Examination revealed severe bilateral optic disc swelling and impaired visual acuity. Laboratory work-up was otherwise unremarkable. Anastrozole was discontinued and over the next month, patient had near-complete resolution of swelling in the right eye and improvement in the left eye. This is the only reported case of optic disc swelling following anastrozole therapy.

Original language	English
Pages (from-to)	268-271
Number of pages	4
Journal	Neuro-Ophthalmology
Volume	38
Issue number	5
DOIs	https://doi.org/10.3109/01658107.2014.924968
State	Published - Oct 1 2014

Keywords

Breast neoplasms
Chemotherapy
Optical coherence tomography
Papilloedema
Vision

ASJC Scopus subject areas

Ophthalmology
Clinical Neurology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3109/01658107.2014.924968

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title = "Bilateral optic disc swelling following anastrozole therapy",

abstract = "A 56-year-old female with early-stage breast cancer, stage IA grade 1 endometrial cancer, and stage IC grade 1 ovarian cancer developed sudden-onset visual changes and right inferior visual field defect following anastrozole therapy. Examination revealed severe bilateral optic disc swelling and impaired visual acuity. Laboratory work-up was otherwise unremarkable. Anastrozole was discontinued and over the next month, patient had near-complete resolution of swelling in the right eye and improvement in the left eye. This is the only reported case of optic disc swelling following anastrozole therapy.",

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AU - Coppes, Oscar Jim Michael

AU - Lukas, Rimas V.

AU - Fleming, Gini F.

AU - Nichols, Jeffrey

AU - Tenney, Meaghan

AU - Bernard, Jacqueline

PY - 2014/10/1

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N2 - A 56-year-old female with early-stage breast cancer, stage IA grade 1 endometrial cancer, and stage IC grade 1 ovarian cancer developed sudden-onset visual changes and right inferior visual field defect following anastrozole therapy. Examination revealed severe bilateral optic disc swelling and impaired visual acuity. Laboratory work-up was otherwise unremarkable. Anastrozole was discontinued and over the next month, patient had near-complete resolution of swelling in the right eye and improvement in the left eye. This is the only reported case of optic disc swelling following anastrozole therapy.

AB - A 56-year-old female with early-stage breast cancer, stage IA grade 1 endometrial cancer, and stage IC grade 1 ovarian cancer developed sudden-onset visual changes and right inferior visual field defect following anastrozole therapy. Examination revealed severe bilateral optic disc swelling and impaired visual acuity. Laboratory work-up was otherwise unremarkable. Anastrozole was discontinued and over the next month, patient had near-complete resolution of swelling in the right eye and improvement in the left eye. This is the only reported case of optic disc swelling following anastrozole therapy.

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KW - Chemotherapy

KW - Optical coherence tomography

KW - Papilloedema

KW - Vision

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Bilateral optic disc swelling following anastrozole therapy

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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