Bilateral subthalamic nucleus deep brain stimulation for advanced PD: Correlation of intraoperative MER and postoperative MRI with neuropathological findings

George J. Counelis, Tanya Simuni, Mark S. Forman, Jurg L. Jaggi, John Q. Trojanowski, Gordon H. Baltuch

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

This postmortem study correlated intraoperative subthalamic nucleus (STN) deep brain stimulation (DBS) placement and postoperative magnetic resonance imaging (MRI) with autopsy findings in a patient who died suddenly 4 days postoperatively from a pulmonary embolism. The study demonstrates that (1) MRI stereotactic localization combined with microelectrode recording (MER) is an accurate way to target STN; (2) multiple MER tracts do not cause significant injury to the brain; and (3) postoperative MRI accurately demonstrates location of the DBS electrodes.

Original languageEnglish (US)
Pages (from-to)1062-1065
Number of pages4
JournalMovement Disorders
Volume18
Issue number9
DOIs
StatePublished - Sep 1 2003

Keywords

  • Deep brain stimulation
  • Magnetic resonance imaging
  • Microelectrode recording
  • Subthalamic nucleus

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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