Biliary Strictures in Hepatic Transplantation

Virginia McDonald, Terence A.S. Matalon*, Suresh K. Patel, Michael C. Brunner, Howard Sankary, Preston Foster, James Williams

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

51 Scopus citations


Between August 1985 and December 1990, 198 liver transplantations were performed. Among 18 patients, 20 biliary strictures were identified, which were categorized as anastomotic (n = 6), nonanastomotic central hilar (n = 8), and nonanastomotic peripheral (n = 6). Pretransplant disease, hepatic artery patency, presence of acute or chronic rejection, and donor cold ischemia times were tabulated for each case. Among the six patients with peripheral strictures, three had sclerosing cholangitis prior to transplantation. Three patients with nonanastomotic strictures experienced chronic rejection. The mean cold ischemia time for patients with nonanastomotic strictures was 9.75 hours versus 8.1 hours for nonstrictured transplants (P = .025). Balloon dilation was performed in 13 patients; follow-up longer than 6 months was available for nine patients. Dilation was successful in four cases. Among the five failures, only one patient has needed surgery. An association was noted between nonanastomotic biliary strictures and prolonged donor cold ischemia time, between peripheral nonanastomotic strictures and pretransplant sclerosing cholangitis, and between nonanastomotic strictures and chronic rejection. Percutaneous balloon dilation was found useful in the treatment of the strictured transplant.

Original languageEnglish (US)
Pages (from-to)533-538
Number of pages6
JournalJournal of Vascular and Interventional Radiology
Issue number4
StatePublished - 1991


  • Bile ducts, interventional procedure, 76.289
  • Bile ducts, stenosis or obstruction, 76.289
  • Liver, interventional procedure, 761.1229
  • Liver, transplantation, 761.458

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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