Binodal, wireless epidermal electronic systems with in-sensor analytics for neonatal intensive care

Ha Uk Chung, Bong Hoon Kim, Jong Yoon Lee, Jungyup Lee, Zhaoqian Xie, Erin M. Ibler, Kun Hyuck Lee, Anthony Banks, Ji Yoon Jeong, Jongwon Kim, Christopher Ogle, Dominic Grande, Yongjoon Yu, Hokyung Jang, Pourya Assem, Dennis Ryu, Jean Won Kwak, Myeong Namkoong, Jun Bin Park, Yechan LeeDo Hoon Kim, Arin Ryu, Jaeseok Jeong, Kevin You, Bowen Ji, Zhuangjian Liu, Qingze Huo, Xue Feng, Yujun Deng, Yeshou Xu, Kyung In Jang, Jeonghyun Kim, Yihui Zhang, Roozbeh Ghaffari, Casey M. Rand, Molly Schau, Aaron Hamvas, Debra E. Weese-Mayer, Yonggang Huang, Seung Min Lee, Chi Hwan Lee, Naresh R. Shanbhag, Amy S. Paller*, Shuai Xu, John A. Rogers

*Corresponding author for this work

Research output: Contribution to journalArticle

34 Scopus citations

Abstract

Existing vital sign monitoring systems in the neonatal intensive care unit (NICU) require multiple wires connected to rigid sensors with strongly adherent interfaces to the skin. We introduce a pair of ultrathin, soft, skin-like electronic devices whose coordinated, wireless operation reproduces the functionality of these traditional technologies but bypasses their intrinsic limitations. The enabling advances in engineering science include designs that support wireless, battery-free operation; real-time, in-sensor data analytics; time-synchronized, continuous data streaming; soft mechanics and gentle adhesive interfaces to the skin; and compatibility with visual inspection and with medical imaging techniques used in the NICU. Preliminary studies on neonates admitted to operating NICUs demonstrate performance comparable to the most advanced clinical-standard monitoring systems.

Original languageEnglish (US)
JournalScience
Volume363
Issue number6430
DOIs
StatePublished - Jan 1 2019

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ASJC Scopus subject areas

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Cite this

Chung, H. U., Kim, B. H., Lee, J. Y., Lee, J., Xie, Z., Ibler, E. M., Lee, K. H., Banks, A., Jeong, J. Y., Kim, J., Ogle, C., Grande, D., Yu, Y., Jang, H., Assem, P., Ryu, D., Kwak, J. W., Namkoong, M., Park, J. B., ... Rogers, J. A. (2019). Binodal, wireless epidermal electronic systems with in-sensor analytics for neonatal intensive care. Science, 363(6430). https://doi.org/10.1126/science.aau0780