Bio-integrated wearable systems: A comprehensive review

Tyler R. Ray, Jungil Choi, Amay J. Bandodkar, Siddharth Krishnan, Philipp Gutruf, Limei Tian, Roozbeh Ghaffari, John A Rogers

Research output: Contribution to journalReview article

10 Citations (Scopus)

Abstract

Bio-integrated wearable systems can measure a broad range of biophysical, biochemical, and environmental signals to provide critical insights into overall health status and to quantify human performance. Recent advances in material science, chemical analysis techniques, device designs, and assembly methods form the foundations for a uniquely differentiated type of wearable technology, characterized by noninvasive, intimate integration with the soft, curved, time-dynamic surfaces of the body. This review summarizes the latest advances in this emerging field of "bio-integrated" technologies in a comprehensive manner that connects fundamental developments in chemistry, material science, and engineering with sensing technologies that have the potential for widespread deployment and societal benefit in human health care. An introduction to the chemistries and materials for the active components of these systems contextualizes essential design considerations for sensors and associated platforms that appear in following sections. The subsequent content highlights the most advanced biosensors, classified according to their ability to capture biophysical, biochemical, and environmental information. Additional sections feature schemes for electrically powering these sensors and strategies for achieving fully integrated, wireless systems. The review concludes with an overview of key remaining challenges and a summary of opportunities where advances in materials chemistry will be critically important for continued progress.

Original languageEnglish (US)
Pages (from-to)5461-5533
Number of pages73
JournalChemical Reviews
Volume119
Issue number8
DOIs
StatePublished - Apr 24 2019

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Materials science
Sensors
Health care
Biosensors
Health
Chemical analysis
Wearable technology

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Ray, T. R., Choi, J., Bandodkar, A. J., Krishnan, S., Gutruf, P., Tian, L., ... Rogers, J. A. (2019). Bio-integrated wearable systems: A comprehensive review. Chemical Reviews, 119(8), 5461-5533. https://doi.org/10.1021/acs.chemrev.8b00573
Ray, Tyler R. ; Choi, Jungil ; Bandodkar, Amay J. ; Krishnan, Siddharth ; Gutruf, Philipp ; Tian, Limei ; Ghaffari, Roozbeh ; Rogers, John A. / Bio-integrated wearable systems : A comprehensive review. In: Chemical Reviews. 2019 ; Vol. 119, No. 8. pp. 5461-5533.
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Ray, TR, Choi, J, Bandodkar, AJ, Krishnan, S, Gutruf, P, Tian, L, Ghaffari, R & Rogers, JA 2019, 'Bio-integrated wearable systems: A comprehensive review' Chemical Reviews, vol. 119, no. 8, pp. 5461-5533. https://doi.org/10.1021/acs.chemrev.8b00573

Bio-integrated wearable systems : A comprehensive review. / Ray, Tyler R.; Choi, Jungil; Bandodkar, Amay J.; Krishnan, Siddharth; Gutruf, Philipp; Tian, Limei; Ghaffari, Roozbeh; Rogers, John A.

In: Chemical Reviews, Vol. 119, No. 8, 24.04.2019, p. 5461-5533.

Research output: Contribution to journalReview article

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Ray TR, Choi J, Bandodkar AJ, Krishnan S, Gutruf P, Tian L et al. Bio-integrated wearable systems: A comprehensive review. Chemical Reviews. 2019 Apr 24;119(8):5461-5533. https://doi.org/10.1021/acs.chemrev.8b00573