Bioactive protein nanoarrays on nickel oxide surfaces formed by dip-pen nanolithography

Jwa Min Nam; Sang Woo Han; Ki Bum Lee; Xiaogang Liu; Mark A. Ratner; Chad A. Mirkin

doi:10.1002/anie.200353203

Bioactive protein nanoarrays on nickel oxide surfaces formed by dip-pen nanolithography

Jwa Min Nam, Sang Woo Han, Ki Bum Lee, Xiaogang Liu, Mark A. Ratner, Chad A. Mirkin^*

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

102 Scopus citations

Abstract

Ink flowing from a pen: Direct-write dippen nanolithography of His-tagged proteins (ubiquitin and thioredoxin) has been used to generate biologically active protein nanoarrays with feature sizes as small as 80 nm on nickel oxide surfaces without the need for an applied electric field. The protein molecules in this system seem to diffuse from the Ni-coated atomic force microscopy (AFM) tips to the Ni-coated substrate (see diagram).

Original language	English (US)
Pages (from-to)	1246-1249
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	43
Issue number	10
DOIs	https://doi.org/10.1002/anie.200353203
State	Published - Feb 27 2004

Keywords

Atomic force microscopy
Nanolithography
Nickel
Protein arrays
Proteins

ASJC Scopus subject areas

Catalysis
Chemistry(all)

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abstract = "Ink flowing from a pen: Direct-write dippen nanolithography of His-tagged proteins (ubiquitin and thioredoxin) has been used to generate biologically active protein nanoarrays with feature sizes as small as 80 nm on nickel oxide surfaces without the need for an applied electric field. The protein molecules in this system seem to diffuse from the Ni-coated atomic force microscopy (AFM) tips to the Ni-coated substrate (see diagram).",

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AU - Nam, Jwa Min

AU - Han, Sang Woo

AU - Lee, Ki Bum

AU - Liu, Xiaogang

AU - Ratner, Mark A.

AU - Mirkin, Chad A.

PY - 2004/2/27

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AB - Ink flowing from a pen: Direct-write dippen nanolithography of His-tagged proteins (ubiquitin and thioredoxin) has been used to generate biologically active protein nanoarrays with feature sizes as small as 80 nm on nickel oxide surfaces without the need for an applied electric field. The protein molecules in this system seem to diffuse from the Ni-coated atomic force microscopy (AFM) tips to the Ni-coated substrate (see diagram).

KW - Atomic force microscopy

KW - Nanolithography

KW - Nickel

KW - Protein arrays

KW - Proteins

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Bioactive protein nanoarrays on nickel oxide surfaces formed by dip-pen nanolithography

Abstract

Keywords

ASJC Scopus subject areas

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