The expression of heat shock proteins in response to cellular stress is mediated by a family of heat shock transcription factors (HSFs). The transcriptional activity of these HSFs is regulated by multiple redundant regulatory mechanisms which ensure the fine tuned expression of heat shock genes. These mechanisms include cis-regulatory domains and trans-acting proteins which modulate HSF activity and control the heat shock response. Heat shock gene expression is also regulated by selective use of various HSFs under distinct developmental and growth conditions.
- Heat shock factors
- Transcriptional activity
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Agricultural and Biological Sciences(all)