TY - JOUR
T1 - Biologic Treatment for Hidradenitis Suppurativa
AU - Flood, Kelsey S.
AU - Porter, Martina L.
AU - Kimball, Alexa B.
N1 - Publisher Copyright:
© 2019, Springer Nature Switzerland AG.
PY - 2019/10/1
Y1 - 2019/10/1
N2 - Patients with hidradenitis suppurativa (HS) are often undertreated and there are limited efficacious therapies available for treating this population. Biologics are an emerging therapeutic modality used in the management of many inflammatory conditions including HS. Implementation of biologics is typically reserved for moderate-to-severe cases or in those cases that are refractory to treatment. Though many biologics have been trialed for use in HS, only one biologic, adalimumab, is currently US FDA (Food and Drug Administration) approved for the treatment of moderate-to-severe HS. Limitations in the use of biologics for HS include the many scoring systems utilized in research studies and the relatively few well-designed, adequately powered clinical trials.
AB - Patients with hidradenitis suppurativa (HS) are often undertreated and there are limited efficacious therapies available for treating this population. Biologics are an emerging therapeutic modality used in the management of many inflammatory conditions including HS. Implementation of biologics is typically reserved for moderate-to-severe cases or in those cases that are refractory to treatment. Though many biologics have been trialed for use in HS, only one biologic, adalimumab, is currently US FDA (Food and Drug Administration) approved for the treatment of moderate-to-severe HS. Limitations in the use of biologics for HS include the many scoring systems utilized in research studies and the relatively few well-designed, adequately powered clinical trials.
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U2 - 10.1007/s40257-019-00439-5
DO - 10.1007/s40257-019-00439-5
M3 - Review article
C2 - 31140067
AN - SCOPUS:85066609163
SN - 1175-0561
VL - 20
SP - 625
EP - 638
JO - American Journal of Clinical Dermatology
JF - American Journal of Clinical Dermatology
IS - 5
ER -