Biological responses to engineered nanomaterials: Needs for the next decade

Catherine J. Murphy*, Ariane M. Vartanian, Franz M. Geiger, Robert J. Hamers, Joel Pedersen, Qiang Cui, Christy L. Haynes, Erin E. Carlson, Rigoberto Hernandez, Rebecca D. Klaper, Galya Orr, Ze'Ev Rosenzweig

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

115 Scopus citations


The interaction of nanomaterials with biomolecules, cells, and organisms is an enormously vital area of current research, with applications in nanoenabled diagnostics, imaging agents, therapeutics, and contaminant removal technologies. Yet the potential for adverse biological and environmental impacts of nanomaterial exposure is considerable and needs to be addressed to ensure sustainable development of nanomaterials. In this Outlook four research needs for the next decade are outlined: (i) measurement of the chemical nature of nanomaterials in dynamic, complex aqueous environments; (ii) real-time measurements of nanomaterial-biological interactions with chemical specificity; (iii) delineation of molecular modes of action for nanomaterial effects on living systems as functions of nanomaterial properties; and (iv) an integrated systems approach that includes computation and simulation across orders of magnitude in time and space.

Original languageEnglish (US)
Pages (from-to)117-123
Number of pages7
JournalACS Central Science
Issue number3
StatePublished - Jun 24 2015

ASJC Scopus subject areas

  • General Chemical Engineering
  • General Chemistry


Dive into the research topics of 'Biological responses to engineered nanomaterials: Needs for the next decade'. Together they form a unique fingerprint.

Cite this