Biomarker-predicted sugars intake compared with self-reported measures in US Hispanics/Latinos: Results from the HCHS/SOL SOLNAS study

Jm Beasley*, M. Jung, N. Tasevska, Ww Wong, Am Siega-Riz, D. Sotres-Alvarez, Md Gellman, Jr Kizer, Pa Shaw, J. Stamler, M. Stoutenberg, L. Van Horn, Aa Franke, J. Wylie-Rosett, Y. Mossavar-Rahmani

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Objective Measurement error in self-reported total sugars intake may obscure associations between sugars consumption and health outcomes, and the sum of 24 h urinary sucrose and fructose may serve as a predictive biomarker of total sugars intake. Design The Study of Latinos: Nutrition & Physical Activity Assessment Study (SOLNAS) was an ancillary study to the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) cohort. Doubly labelled water and 24 h urinary sucrose and fructose were used as biomarkers of energy and sugars intake, respectively. Participants' diets were assessed by up to three 24 h recalls (88 % had two or more recalls). Procedures were repeated approximately 6 months after the initial visit among a subset of ninety-six participants. Setting Four centres (Bronx, NY; Chicago, IL; Miami, FL; San Diego, CA) across the USA. Subjects Men and women (n 477) aged 18-74 years. Results The geometric mean of total sugars was 167·5 (95 % CI 154·4, 181·7) g/d for the biomarker-predicted and 90·6 (95 % CI 87·6, 93·6) g/d for the self-reported total sugars intake. Self-reported total sugars intake was not correlated with biomarker-predicted sugars intake (r=-0·06, P=0·20, n 450). Among the reliability sample (n 90), the reproducibility coefficient was 0·59 for biomarker-predicted and 0·20 for self-reported total sugars intake. Conclusions Possible explanations for the lack of association between biomarker-predicted and self-reported sugars intake include measurement error in self-reported diet, high intra-individual variability in sugars intake, and/or urinary sucrose and fructose may not be a suitable proxy for total sugars intake in this study population.

Original languageEnglish (US)
Pages (from-to)3256-3264
Number of pages9
JournalPublic Health Nutrition
Issue number18
StatePublished - Dec 1 2016


  • Doubly labelled water
  • Hispanics/Latinos
  • Keywords Sugars
  • Self-report
  • Urinary sucrose and fructose biomarkers

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Nutrition and Dietetics
  • Medicine (miscellaneous)


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