This study showed how tensile stress and shear stress regulate smooth muscle cell (SMC) proliferation and neointimal formation in experimental vein grafts, and how to engineer a vein graft to prevent these pathological events. Results demonstrate that mechanical stresses play a role in vein graft remodeling, and these stresses as well as their pathological consequences can be modulated by using a biomechanical engineering approach.
|Original language||English (US)|
|Journal||Annals of Biomedical Engineering|
|Issue number||SUPPL. 1|
|State||Published - Dec 1 2000|
ASJC Scopus subject areas
- Biomedical Engineering