Abstract
This study showed how tensile stress and shear stress regulate smooth muscle cell (SMC) proliferation and neointimal formation in experimental vein grafts, and how to engineer a vein graft to prevent these pathological events. Results demonstrate that mechanical stresses play a role in vein graft remodeling, and these stresses as well as their pathological consequences can be modulated by using a biomechanical engineering approach.
| Original language | English (US) |
|---|---|
| Journal | Annals of Biomedical Engineering |
| Volume | 28 |
| Issue number | SUPPL. 1 |
| State | Published - Dec 1 2000 |
ASJC Scopus subject areas
- Biomedical Engineering