Biomechanical basis of vascular tissue engineering

Shu Liu*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


This study showed how tensile stress and shear stress regulate smooth muscle cell (SMC) proliferation and neointimal formation in experimental vein grafts, and how to engineer a vein graft to prevent these pathological events. Results demonstrate that mechanical stresses play a role in vein graft remodeling, and these stresses as well as their pathological consequences can be modulated by using a biomechanical engineering approach.

Original languageEnglish (US)
JournalAnnals of Biomedical Engineering
Issue numberSUPPL. 1
StatePublished - Dec 1 2000

ASJC Scopus subject areas

  • Biomedical Engineering


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