Biomedical nanotechnology for molecular imaging, profiling, and drug targeting

Gloria J. Kim; Ruth M. O'Regan; Shuming Nie

doi:10.1109/iembs.2005.1616513

Biomedical nanotechnology for molecular imaging, profiling, and drug targeting

Gloria J. Kim^*, Ruth M. O'Regan, Shuming Nie

^*Corresponding author for this work

Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

8 Scopus citations

Abstract

Nanometer-sized particles have novel optical, electronic, and structural properties that are not available from either individual molecules or bulk solids. When linked with tumor targeting ligands such as monoclonal antibodies, these nanoparticles can be used to target tumor antigens (biomarkers) as well as tumor vasculatures with high affinity and specificity. In the "mesoscopic" size range of 10-100 nm (diameter), nanoparticles also have more surface areas and functional groups that can be linked to multiple diagnostic (e.g., optical, radioisotopic, or magnetic) and therapeutic (e.g., anticancer) agents. In this article, we briefly discuss the use of bioconjugated nanoparticles for delivery and targeting of anticancer drugs.

Original language	English (US)
Title of host publication	Proceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	714-716
Number of pages	3
ISBN (Print)	0780387406, 9780780387409
DOIs	https://doi.org/10.1109/iembs.2005.1616513
State	Published - 2005
Event	2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005 - Shanghai, China Duration: Sep 1 2005 → Sep 4 2005

Publication series

Name	Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume	7 VOLS
ISSN (Print)	0589-1019

Other

Other	2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005
Country/Territory	China
City	Shanghai
Period	9/1/05 → 9/4/05

ASJC Scopus subject areas

Signal Processing
Biomedical Engineering
Computer Vision and Pattern Recognition
Health Informatics

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10.1109/iembs.2005.1616513

Cite this

Kim, G. J., O'Regan, R. M., & Nie, S. (2005). Biomedical nanotechnology for molecular imaging, profiling, and drug targeting. In Proceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005 (pp. 714-716). [1616513] (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings; Vol. 7 VOLS). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/iembs.2005.1616513

Kim, Gloria J. ; O'Regan, Ruth M. ; Nie, Shuming. / Biomedical nanotechnology for molecular imaging, profiling, and drug targeting. Proceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005. Institute of Electrical and Electronics Engineers Inc., 2005. pp. 714-716 (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings).

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abstract = "Nanometer-sized particles have novel optical, electronic, and structural properties that are not available from either individual molecules or bulk solids. When linked with tumor targeting ligands such as monoclonal antibodies, these nanoparticles can be used to target tumor antigens (biomarkers) as well as tumor vasculatures with high affinity and specificity. In the {"}mesoscopic{"} size range of 10-100 nm (diameter), nanoparticles also have more surface areas and functional groups that can be linked to multiple diagnostic (e.g., optical, radioisotopic, or magnetic) and therapeutic (e.g., anticancer) agents. In this article, we briefly discuss the use of bioconjugated nanoparticles for delivery and targeting of anticancer drugs.",

author = "Kim, {Gloria J.} and O'Regan, {Ruth M.} and Shuming Nie",

year = "2005",

doi = "10.1109/iembs.2005.1616513",

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series = "Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings",

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booktitle = "Proceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005",

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note = "2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005 ; Conference date: 01-09-2005 Through 04-09-2005",

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Kim, GJ, O'Regan, RM & Nie, S 2005, Biomedical nanotechnology for molecular imaging, profiling, and drug targeting. in Proceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005., 1616513, Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, vol. 7 VOLS, Institute of Electrical and Electronics Engineers Inc., pp. 714-716, 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005, Shanghai, China, 9/1/05. https://doi.org/10.1109/iembs.2005.1616513

Biomedical nanotechnology for molecular imaging, profiling, and drug targeting. / Kim, Gloria J.; O'Regan, Ruth M.; Nie, Shuming.
Proceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005. Institute of Electrical and Electronics Engineers Inc., 2005. p. 714-716 1616513 (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings; Vol. 7 VOLS).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

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AU - O'Regan, Ruth M.

AU - Nie, Shuming

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AB - Nanometer-sized particles have novel optical, electronic, and structural properties that are not available from either individual molecules or bulk solids. When linked with tumor targeting ligands such as monoclonal antibodies, these nanoparticles can be used to target tumor antigens (biomarkers) as well as tumor vasculatures with high affinity and specificity. In the "mesoscopic" size range of 10-100 nm (diameter), nanoparticles also have more surface areas and functional groups that can be linked to multiple diagnostic (e.g., optical, radioisotopic, or magnetic) and therapeutic (e.g., anticancer) agents. In this article, we briefly discuss the use of bioconjugated nanoparticles for delivery and targeting of anticancer drugs.

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Kim GJ, O'Regan RM, Nie S. Biomedical nanotechnology for molecular imaging, profiling, and drug targeting. In Proceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005. Institute of Electrical and Electronics Engineers Inc. 2005. p. 714-716. 1616513. (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings). doi: 10.1109/iembs.2005.1616513

Biomedical nanotechnology for molecular imaging, profiling, and drug targeting

Abstract

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