Bioresorbable Metals for Biomedical Applications: From Mechanical Components to Electronic Devices

Hanjun Ryu, Min Ho Seo, John A. Rogers*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Bioresorbable metals and metal alloys are of growing interest for myriad uses in temporary biomedical implants. Examples range from structural elements as stents, screws, and scaffolds to electronic components as sensors, electrical stimulators, and programmable fluidics. The associated physical forms span mechanically machined bulk parts to lithographically patterned conductive traces, across a diversity of metals and alloys based on magnesium, zinc, iron, tungsten, and others. The result is a rich set of opportunities in healthcare materials science and engineering. This review article summarizes recent advances in this area, starting with an historical perspective followed by a discussion of materials options, considerations in biocompatibility, and device applications. Highlights are in system level bioresorbable electronic platforms that support functions as diagnostics and therapeutics in the context of specific, temporary clinical needs. A concluding section highlights challenges and emerging research directions.

Original languageEnglish (US)
JournalAdvanced Healthcare Materials
DOIs
StateAccepted/In press - 2021

Keywords

  • biomedical implants
  • bioresorbable electronics
  • bioresorbable metals
  • bioresorbable structures
  • transient electronics

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering
  • Pharmaceutical Science

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